NIP-322 / Nissan Chemical Corp - LARVOL DELTA

NIP-322, a novel sepiapterin reductase specific inhibitor without tolerance and safety concerns for the treatment of osteoarthritis pain (Neuroscience 2022) - "These studies demonstrate that NIP-322 has the difference from prior Q-compounds in chemical and biological property, suggesting a rationale for no toxicological findings in 4-week dog toxicity study. We concluded that NIP-322 will be a promising candidate option for OA patients with a favorable profile that avoids the tolerance and dyscoordination."

Clinical • CNS Disorders • Musculoskeletal Pain • Pain