nanoHYP (nanohypericin +alk.phosphatase) / Aphios - LARVOL DELTA

Non-biodegradable polymeric waste pyrolysis for energy recovery. (PubMed, Heliyon) - "Nanocatalysis closes the gap between homo and heterogeneous catalyses while combines their advantageous characteristics and positive aspects, reducing the respective drawbacks. During the current nanohype, nanostructured catalysts are esteemed materials and their exploration provide promising solutions for challenges from the perspective of cost and factors influencing catalytic activity, due to their featured high surface area to volume ratio which render enhanced properties with respect to the bulk catalyst."

Journal • Review

Photothermal Depletion of Cancer-Associated Fibroblasts Normalizes Tumor Stiffness in Desmoplastic Cholangiocarcinoma. (PubMed, ACS Nano) - "To normalize tumor mechanics, we propose a physical strategy based on remotely light activated nanohyperthermia to modulate the tumor micro-environment...The preferential uptake of GIONF by CAF allowed targeting this cell population, which resulted in a significant early reduction of tumor stiffness followed by tumor regression. In conclusion, our study highlights a spatially and temporally controlled physical strategy, GIONF-mediated photothermal therapy, to deplete CAF and normalize the tumor mechanics that may apply to desmoplastic cancer and CCA treatment."

Journal • Biliary Cancer • Cholangiocarcinoma • Gastrointestinal Cancer • Oncology • Solid Tumor

Critical behavior of ensembles of superparamagnetic nanoparticles with dispersions of magnetic parameters. (PubMed, J Phys Condens Matter) - "...Critical behavior of the spontaneous magnetization is experimentally determined for the ensemble of nanoparticles of lanthanum-strontium manganites, which are considered as promising materials for self-controlled magnetic nanohyperthermia...Theoretical background for the use of the "effective Curie temperature for the ensemble of nanoparticles" concept is proposed for ensembles of particles with dispersion of their Curie temperature. Based on the results obtained, various strategies to develop novel biomedical applications, in particular those suitable for noninvasive temperature monitoring, are discussed."

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