MQI-181
/ Mabqi
- LARVOL DELTA
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November 04, 2025
Next-generation tumor-specific anti-CD30 ADC as a new therapy in hemato-oncology
(ASH 2025)
- "Tournilhac, Blood Advances2025) demonstrated that high circulating sCD30 levels were associated with poor prognosis in patientstreated with Brentuximab Vedotin (BV)...MQI-181 is a next-generation anti-CD30 therapy with high clinical potential, able tospecifically target the tumor site while avoiding its capture by circulating CD30. In vivo, MQI-181demonstrated complete tumor regression in a preclinical lymphoma cancer model and superiority overBV in the presence of soluble CD30. The Phase I trial is now under planification."
Hematological Malignancies • Hodgkin Lymphoma • Lymphoma • Non-Hodgkin’s Lymphoma • Oncology
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