peptide YY3-36 intranasal / Adhera Therap - LARVOL DELTA

Serum lipase activity and concentration during intravenous infusions of GLP-1 and PYY3-36 and after ad libitum meal ingestion in overweight men. (PubMed) - Physiol Rep - "Infusions of GLP-1 and PYY3-36, separately or in combination, did not increase serum lipase. However, a small increase in serum lipase may occur in response to a meal."

Journal • Biosimilar • Obesity

Endocrine Modulation of Olfactory Responsiveness: Effects of the Orexigenic Hormone Ghrelin. (PubMed) - "In contrast to the effects of the "hunger" hormone ghrelin, the short-term "satiety" hormone PYY3-36 did not affect olfactory responsiveness. The results demonstrate that ghrelin, which signals acute hunger, renders the olfactory system more responsive to odors."

Journal • Biosimilar

Effects and mechanisms of auricular vagus nerve stimulation on high-fat-diet-induced obese rats. (PubMed) - "AVNS was more effective in reducing body weight and causing visceral fat loss. Biochemical tests found more NE released in the serum and more β3-adrenoceptor and UCP1 expression in the BAT. All of these features suggested that energy expenditure might play an important role in obesity management by AVNS."

Journal • Biosimilar • Obesity

Degradation of the Anorexic Hormone Peptide YY (clinicaltrials.gov) - P0; N=8; Completed; Sponsor: Hvidovre University Hospital

New trial • Biosimilar

Appetite and Energy Intake Responses to Acute Energy Deficits in Females Versus Males. (PubMed) - "Women exhibit compensatory appetite, gut hormone and food intake responses to acute energy restriction but not in response to an acute bout of exercise. Additionally, men and women appear to exhibit similar acylated ghrelin and PYY3-36 responses to exercise-induced energy deficits. These findings advance understanding regarding the interaction between exercise and energy homeostasis in women."

Journal • Biosimilar