mesalazine controlled-release tablets / Generic mfg. - LARVOL DELTA

Design and validation of a robust stability-indicating reversed-phase HPLC method for quantification of mesalamine in formulated drug products. (PubMed, BMC Chem) - "Forced degradation studies under acidic, basic, oxidative, thermal, and photolytic stress confirmed the method's specificity and stability-indicating capability. Assay of a commercial mesalamine tablet (Mesacol®, 800 mg label claim) showed a recovery of 99.91%, validating the method's applicability for routine quality control and regulatory compliance."

Journal

A flavonoid rich standardized extract of Glycyrrhiza glabra protects intestinal epithelial barrier function and regulates the tight-junction proteins expression. (PubMed, BMC Complement Med Ther) - "The study findings support the protective action of FREG on intestinal epithelial barrier integrity indicating its potential in protecting from implications of leaky gut."

Journal • CNS Disorders • Gastroenterology • Gastrointestinal Cancer • Gastrointestinal Disorder • Immunology • Inflammation • Inflammatory Bowel Disease • Oncology • Psychiatry • Ulcerative Colitis • MPO • TNFA

Mesacol: The effect of mesalazine on molecular pathways ofcell adhesion in ulcerative colitis Mesacol: Effekt von Mesalazin auf molekulareZelladhäsionspathways bei Colitis ulcerosa (clinicaltrialsregister.eu) - P2; N=12; Ongoing; Sponsor: Medizinische Universität Wien, Universitätsklinik für Innere Medizin 3, Abteilung für Gastroenterologie und Hepatologie

New P2 trial