LY2881835
/ Eli Lilly
- LARVOL DELTA
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January 19, 2019
Design, synthesis and evaluation of a series of novel phenylpropanoic acid derivatives agonists for the FFA1.
(PubMed, Chem Biol Drug Des)
- "Aiming to develop novel potent FFA1 agonists, a new series of phenylpropionic acid derivatives were designed and synthesized on the basis of the modification of chemical cement of TAK-875, AMG-837, and LY2881835. Herein, we reported the discovery and optimization of a series of potent FFA1 agonists. The discovery supported further exploration surrounding this scaffold."
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