TJ108 / Phrontline Biopharma, Samsung - LARVOL DELTA

Longitudinal plasma phosphorylated neurofilament-heavy chain levels in oxaliplatin-induced peripheral neuropathy: a prospective multi-institutional exploratory study. (PubMed, Cancer Chemother Pharmacol) - "Although longitudinal plasma pNF-H measurement was technically feasible, pNF-H did not function as a clinically meaningful biomarker for oxaliplatin-induced peripheral neuropathy. These findings may reflect a pathophysiological mismatch between dorsal root ganglion neuronal cell body injury and the axon-oriented biological specificity of pNF-H."

Biomarker • Clinical • Journal • Colorectal Cancer • Oncology • Pain • Solid Tumor • NEFH