triamcinolone acetonide injection suspension / Generic mfg. - LARVOL DELTA

Punch Excision Therapy for the Treatment of Keloids: A Systematic Review (CDA 2025) - "Moreover, one case series study (n=30) reported a 69.6% decrease in Patient and Observer Scar Assessment Scale (POSAS) 2.0 scores after punch excision therapy combined with triamcinolone acetonide injection... Punch excision therapy shows promising efficacy for keloid improvement, being cost-effective and accessible. However, further comparative studies with standardized treatment protocols, measurement tools, and long-term follow-up are needed to fully understand its benefits and role in the comprehensive management of keloids."

Review • Fibrosis • Pain • IL6 • TGFB1

Esophageal stricture due to corrosive substance ingested and delayed management: A case report. (PubMed, Trauma Case Rep) - "Despite 14 times of endoscopic performed combined with dilation and Triamcinolone Acetonide injection, the esophageal and pyloric strictures recurrence occurred several times...Local steroids are less likely to cause challenges during esophageal dilatation than systemic or oral steroids. Corrosive substance ingestion negatively impacts the upper gastrointestinal system; one of the case is esophageal stricture, which requires lengthy management of lumen narrowing recurrence."

Journal

An Effective Auricular Keloids Management Method: Excision of the Original Lesion and Postoperative Corticosteroids. (PubMed, Aesthetic Plast Surg) - "For keloids with diverse morphologies and anatomic locations, adopting individualized combined treatment involving surgical excision and intralesional triamcinolone acetonide injections can achieve the reconstruction of auricle morphology and maintain a long-term therapeutic effect."

Journal • Fibrosis

Formulation, in-vitro characterization and clinical evaluation of curcumin in-situ gel for treatment of oral submucosal fibrosis (OSF). (PubMed, Int J Pharm) - P=N/A | "This study demonstrates that curcumin thermosensitive in-situ gels, as a novel dosing regimen, can achieve painless management of OSF, which is also the novelty of this work."

Journal • Preclinical • Fibrosis • Gastrointestinal Disorder • Immunology • Oncology • Pain

Elucidating medication waste for outpatient clinic procedures with intralesional triamcinolone (SID 2025) - "We conducted a retrospective chart review for patients receiving intralesional steroid injections with Kenalog-40 or Kenalog-10 at our academic institution from 01/01/2020–12/31/2023 for the treatment of scars, keloids, or different types of alopecia. Our results highlight an urgent opportunity to reduce unnecessary medical waste from single-use medications and the importance of considering how our daily practice affects our environmental impact. Encouraging sustainable practices such as optimizing medication dosing and preparation, implementing a return program for unused medication, and increasing awareness may help minimize medical waste in dermatology."

Clinical • Alopecia • Dermatology • Fibrosis • Immunology

Combining orbital intensity modulated radiation therapy with periorbital triamcinolone acetonide injection for Graves' orbitopathy. (PubMed, Int J Ophthalmol) - "The combination therapy demonstrates significant effectiveness in treating patients with GO who experienced severe ocular inflammation and have previous GPT failure. Noticeable improvement is observed as early as one month after initiating radiation therapy, and patients with more severe inflammatory states showes greater benefit from the treatment."

Journal • Inflammation • Ocular Inflammation • Ophthalmology • Thyroid Eye Disease

A case of retinal phlebitis complicated by punctate inner choroidopathy-like lesion (ARVO 2025) - "The patient was started on oral prednisolone (PSL) therapy...Layman Abstract (optional): Provide a 50-200 word description of your work that non-scientists can understand. Describe the big picture and the implications of your findings, not the study itself and the associated details."

Clinical • Ocular Inflammation • Ophthalmology

Recurrent uveitic macular edema managed with intravitreal faricimab injection. (PubMed, J Ophthalmic Inflamm Infect) - "The findings of this case hint towards the potential simultaneous effect of angiopoietin-2 blockade along with vascular endothelia growth factor A inhibition by faricimab in managing treatment-resistant UME. Nonetheless, more studies focusing on the role of intravitreal faricimab in UME are required."

Journal • Macular Edema • Ocular Inflammation • Ophthalmology • Retinal Disorders • Vasculitis

Efficacy of Combined 595-nm Pulsed Dye Laser and Intralesional Corticosteroids Versus Intralesional Corticosteroids Alone for Treating Postmastectomy Hypertrophic Scars and Keloids in Transgender Men: A Randomized Controlled Trial. (PubMed, J Cosmet Dermatol) - "The addition of 595-nm PDL to IL TAC may provide more favorable outcomes for treating postmastectomy HTS and keloids among TM."

Clinical • Journal • Fibrosis

Case report: Two cases of multiple evanescent white dot syndrome with transient night blindness. (PubMed, Front Ophthalmol (Lausanne)) - "SubTenon's triamcinolone acetonide injection was administered, and 3 months after the injection, the night blindness, ffERG abnormalities, and EZ loss had resolved, but the enlarged blind spot remained. MEWDS rarely causes transient night blindness due to extensive rod dysfunction. However, outer retinal layer damage is reversible, with night blindness typically resolving within a few months."

Journal • Ophthalmology

Epstein-Barr Virus Associated Frosted Branch Angiitis. (PubMed, Retin Cases Brief Rep) - "Bilateral FBA may present following EBV infection and responds well to corticosteroids and antiviral therapy."

Journal • CNS Disorders • Epstein-Barr Virus Infections • Genetic Disorders • Infectious Disease • Inflammation • Ocular Inflammation • Pain • Retinal Disorders • Vasculitis

Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough (clinicaltrials.gov) - P=N/A | N=50 | Recruiting | Sponsor: University of Alabama at Birmingham | Trial primary completion date: Oct 2024 ➔ Oct 2026

Trial primary completion date • Cough • Respiratory Diseases

An evaluation of surgical excision versus steroid injection for the management of ganglion cysts. (PubMed, Sci Rep) - "Patients were divided into two groups: Group A underwent surgical excision and Group B received aspiration followed by 40 mg of intralesional triamcinolone acetonide injection...Surgical excision demonstrated significantly better outcomes, with higher success and lower recurrence rates than aspiration and steroid injection for the management of ganglion cysts. Therefore, this should be considered the preferred treatment option."

Clinical • Journal • Oncology • Pain

Graft-repositioning technique using infusion and small bubbles during Descemet's membrane endothelial keratoplasty. (PubMed, BMC Ophthalmol) - "The described technique enables the safe and feasible repositioning and unfolding of the DMEK graft."

Journal • Ocular Inflammation • Ophthalmology • Transplantation • Uveitis

Comparing the Efficacy of Combined Intralesional Triamcinolone Acetonide With Topical Calcipotriol Versus Intralesional Triamcinolone Acetonide Monotherapy in Scalp and Beard Alopecia Areata: Results From a Randomized Single-Blinded Clinical Trial. (PubMed, J Cutan Med Surg) - "The addition of topical calcipotriol to IL steroid showed increased efficacy in scalp patches of AA but not in beard patches. Also, the incidence of atrophy was lower in the combination group."

Journal • Monotherapy • Alopecia • Dermatology • Immunology

A curative effect evaluation of intensity-modulated radiation therapy combined with periorbital triamcinolone acetonide injection in treating thyroid eye disease patients with active extraocular muscle but low CAS. (PubMed, Sci Rep) - "Patients with hyperthyroidism had worse effect than those with normal thyroid function. The higher the CAS, the better the effect."

Journal • Observational data • Retrospective data • Endocrine Disorders • Ophthalmology • Thyroid Eye Disease

Coats-Like reaction post-vitreoretinal surgery for PDR managed with laser photocoagulation and adjunctive intravitreal steroids- a case report. (PubMed, BMC Ophthalmol) - "This case highlights the occurrence of a Coats-like response following vitreoretinal surgery for PDR, potentially triggered by retinal ischemia and surgical inflammation. Timely intervention with laser photocoagulation, and adjunctive intravitreal corticosteroids can effectively manage such responses."

Journal • Achromatopsia • Cardiovascular • Cataract • Diabetes • Diabetic Retinopathy • Hypertension • Inflammation • Metabolic Disorders • Ophthalmology • Retinal Disorders • Type 2 Diabetes Mellitus

Transient anterior chamber intraocular lens opacification by triamcinolone acetonide following intravitreal injection. (PubMed, GMS Ophthalmol Cases) - "Conservative management led to spontaneous clearing of intraocular lens (IOL) and resolution of CME in 4 weeks. Opacification of ACIOL following IVTA injection is a rare complication which can be seen in eyes with compromised zonular/capsular bag integrity."

Journal • Cataract • Macular Edema • Ophthalmology

Intravitreal steroid-associated central serous chorioretinopathy. (PubMed, BMJ Case Rep) - "Both cases showed complete resolution of cystoid oedema after intravitreal triamcinolone acetonide injection, but there was a progressive increase in neurosensory detachment (NSD), leading to a suspicion of CSC...The first case was treated with focal laser, and the second one was treated with oral eplerenone...This report adds to the evidence that intravitreal steroids can indeed cause acute CSC. A high index of suspicion for CSC should be maintained in cases where NSD increases following intravitreal steroid administration."

Journal • Diabetic Macular Edema • Macular Edema • Ophthalmology • Retinal Disorders • Retinal Vein Occlusion

Platelet-Rich Plasma versus Corticosteroid Injection for the Treatment of de Quervain Tenosynovitis: A Randomised Control Open Label Equivalence Trial. (PubMed, J Hand Surg Asian Pac Vol) - "Adult patients aged 18-60 were randomly assigned to receive either ultrasound-guided triamcinolone acetonide injections or autologous PRP in the first extensor compartment...Both PRP and CS are safe and equally effective treatments for DQ. Level of Evidence: Level I (Therapeutic)."

Journal • Inflammation • Pain

Sonographically-navigated frozen shoulder release (S-FSR): A modified technique for sonographically-navigated, in-office hydrodilatation of adhesive capsulitis. (PubMed, Shoulder Elbow) - "Furthermore, we outline our protocol for patient preparation with preprocedural diazepam 5 mg and Hydrocodone 5 mg-Acetaminophen 325 mg, one tablet each. During the procedure, we inject a solution of 10 mL lidocaine mixed with 2 mL of 40 mg/mL triamcinolone acetonide injection (80 mg total) through an anterior approach at the level of the rotator interval for pain control...We conclude the procedure with hydrodilatation of the GH joint (GHJ) through the posterior approach with approximately 50 mL of 0.9% normal saline, or until an expansion and release of the GH joint is visualized under ultrasound visualization. A full instruction video can be found at: https://www.youtube.com/watch?v = ZNB0R0hkeok&ab_channel = DrJorgeA.Gonzalez."

Journal • Pain

Morphological and Histological Changes Following Triamcinolone Injection Alone or Mixed Injection of Triamcinolone and Botulinum Toxin in Upper Eyelid. (PubMed, J Craniofac Surg) - "Triamcinolone acetonide combined with BTXA showed better results in decreasing upper eyelid height than TA alone in normal monkey eyelids due to its predictable effect. In addition, there were no differences between the side effects and the histology results between the 4 groups. Therefore, TA combined with BTXA may become a promising treatment for selective thyroid eyelid retraction and could offer an alternative to surgery and its complications."

Journal

Long-term outcomes of intravenous corticosteroid pulse therapy for rapidly progressive alopecia areata: A single-center retrospective analysis of 106 cases and usefulness evaluation of a scoring system originally designed for half-year efficacy prediction for extended periods. (PubMed, J Dermatol) - "With additional interventions represented by intralesional triamcinolone acetonide injection with or without topical potent corticosteroid for those who insufficiently responded at 6 months after IVPT, 64.2%, 14.2%, and 21.7% of the patients respectively achieved good response (GR; SALT score ≤25), moderate response (MR; 25 < SALT score <75), and poor response (PR; 75 ≤ SALT score) 1 year after IVPT...The revised scoring system adding the absence of preceding infectious diseases as one factor successfully predicted the occurrence of the relapse in our cohort (P = 0.002). Taken together, previously unreported real-world efficacy of IVPT to RP-AA was elucidated with the invention of a tool putatively enabling optimal long-term management."

Journal • Retrospective data • Alopecia • Immunology • Infectious Disease

Ultrasound-guided intralesional steroid injection in idiopathic granulomatous mastitis as a newer first-line treatment option with promising therapeutic efficacy (EUSOBI 2024) - "The LSI protocol involved an intralesional triamcinolone acetonide injection into the ultrasound-detected loculated collections, mastitis, fistulous tracts, and sinuses every 4-6 weeks till their optimal response. Patients receiving combined LSI and OST were administered low-dose oral methylprednisolone (<15mg) along with intralesional steroid injections...It can be used either as a sole treatment option or in combination with oral steroids. Compared with systemic oral steroid therapy, intralesional steroid injections could be considered a new treatment modality with fewer side effects."

Clinical

Efficacy of Nd:YAG Laser and Intralesional Triamcinolone Injection Combination Therapy in the Postoperative Management of Keloids. (PubMed, Aesthetic Plast Surg) - "Dual therapy involving TAC injection and Nd:YAG laser treatment was more effective than TAC injection alone for managing keloid scars after surgery. This combination therapy showed better outcomes in preventing keloid recurrence and improving scar status at 12 months after operation, along with significant improvements in patient-reported outcomes."

Combination therapy • Journal • Fibrosis • Immunology