triamcinolone acetonide injection suspension / Generic mfg. - LARVOL DELTA

Hyaluronic acid injection aided by triamcinolone acetonide for treating periorbital depressed scars: A retrospective study. (PubMed, Medicine (Baltimore)) - "At 1-year follow-up, only 2 cases had reappearance of indentation of the scar (both <1 mm). Triamcinolone Acetonide injections combined with HA is safe and feasible for the treatment of periorbital scarring and can effectively improve the appearance of patients with periorbital scarring."

Journal • Retrospective data • Dermatology

Short-Term Outcomes of Intravitreal Brolucizumab Injection and Sub-Tenon Injection of Triamcinolone Acetonide for Diabetic Macular Edema: A Pilot Study. (PubMed, J Vitreoretin Dis) - " Combination therapy with intravitreal brolucizumab and sub-Tenon triamcinolone acetonide may offer anatomic benefits in patients with DME, requiring fewer injections. Further evaluation using larger, prospectively designed studies is warranted to confirm its functional efficacy and long-term safety."

Journal • Diabetic Macular Edema • Inflammation • Ophthalmology

Rapidly Progressive Bilateral Syphilitic Optic Neuritis in an Elderly Patient: A Case Report. (PubMed, Cureus) - "Significant and concerning findings indicate that despite early diagnosis confirmed by positive serological tests (RPR 2.9 R.U., TPHA 6.24 R.U.) and prompt initiation of high-dose intravenous benzylpenicillin potassium therapy (18 million units daily for 14 days), visual function recovery was minimal, with persistent severe visual impairment in both eyes at one-month follow-up...Advanced therapeutic interventions including sub-Tenon triamcinolone acetonide injections and oral amoxicillin supplementation were employed because RPR titers had not turned negative, and vision improvement had not been achieved...Hence, patient age and initial disease severity are significant prognostic factors, and, unquestionably, this represents an important clinical consideration for ophthalmologists managing ocular syphilis. For this reason, early recognition and aggressive treatment initiation remain crucial, though visual recovery expectations should be tempered in elderly patients..."

Journal • Genetic Disorders • Infectious Disease • Ocular Inflammation • Ophthalmology • Optic Neuritis • Retinal Disorders • Uveitis

Management of sequential intraocular lens dislocations in a single eye following prior complicated cataract surgery: A case report. (PubMed, SAGE Open Med Case Rep) - "Subtenon triamcinolone acetonide injection partially resolved the cystoid macular edema, and the visual outcome was satisfactory. Understanding this case may aid in surgical planning and facilitate effective postoperative management of complications, ultimately leading to an optimal visual outcome."

Journal • Cataract • Macular Edema • Ophthalmology • Retinal Disorders

Retinal phlebitis complicated by punctate inner choroidopathy-like lesions: a case report. (PubMed, Am J Ophthalmol Case Rep) - "Treatment with oral prednisolone and sub-Tenon triamcinolone acetonide injections controlled the inflammation, and intravitreal aflibercept injections managed the CNV. At the two-year follow-up, the corrected visual acuity improved to 1.2. The distribution of lesions along the retinal veins suggests that this case represents a presentation of PIC-like lesions secondary to retinal phlebitis."

Journal • Inflammation • Ophthalmology • Retinal Disorders

Subconjunctival Triamcinolone Acetonide in the Treatment of Non-necrotizing, Non-infectious Anterior Scleritis. (PubMed, Cureus) - "STI provides effective local disease control and symptom relief in non-necrotizing, non-infectious anterior scleritis, while reducing systemic treatment burden. They appear to be a safe, cost-effective adjunct, though careful patient selection and monitoring for IOP elevation are essential."

Journal • Anesthesia • Cardiovascular • Cataract • Glaucoma • Inflammation • Ocular Inflammation • Ophthalmology • Pain • Scleritis

Alembic Pharmaceuticals Limited (Alembic) announced that it has received final approval from the US Food & Drug Administration (USFDA) for its Abbreviated New Drug Application (ANDA) Triamcinolone Acetonide Injectable Suspension USP, 40 mg/mL Single-Dose Vials, 200 mg/5 mL and 400 mg/10 mL (40 mg/mL) Multiple-Dose Vials. (Indian Pharma Post) - "Triamcinolone Acetonide injectable suspension USP is indicated for various autoimmune, inflammatory, and other conditions where oral therapy is not feasible."

ANDA • Immunology • Inflammation

Resolution of lamellar macular hole after suprachoroidal triamcinolone injections for cystoid macular edema caused by retinal vein occlusion: A case report. (PubMed, Medicine (Baltimore)) - "Suprachoroidal triamcinolone acetonide injections may offer a non-surgical treatment option for LMHs associated with CME secondary to retinal vein occlusion. Further research is needed to confirm these findings and determine the efficacy and safety of this approach in a larger patient population."

Journal • Macular Edema • Ophthalmology • Retinal Disorders • Retinal Vein Occlusion

Efficacy and safety of polynucleotide injection for the treatment of hypertrophic scars and keloids on abdomen: a randomized, double-blinded, split-scar study (EADV 2025) - "The secondary objective is to assess the potential side effects of PDRN treatment in comparison to intralesional corticosteroid injections (triamcinolone acetonide)... Polynucleotide (PN) injections are effective in reducing scar height and pigmentation in hypertrophic scars and keloids. The PN treatment showed superior outcomes compared to intralesional corticosteroid injections, especially in terms of pigmentation and hemoglobin index. These findings suggest that PN could be a promising alternative for managing scars."

Clinical • Fibrosis • Inflammation • ADORA2A

Three-year outcomes of cystotomy for cystoid macular edema secondary to retinal vein occlusion. (PubMed, PLoS One) - "Clinical parameters such as age, sex, best-corrected visual acuity (BCVA), central retinal thickness (CRT), number of treatments (anti-vascular endothelial growth factor injections, sub-Tenon triamcinolone acetonide injections, microaneurysm photocoagulation, and pars plana vitrectomy), number of outpatient visits, presence of fibrinogen clot removal, and recurrence were retrospectively analyzed...Recurrence was observed in eight eyes. Cystotomy appeared to be a promising surgical option for managing refractory RVO-ME."

Journal • Observational data • Retrospective data • Cardiovascular • Macular Edema • Ophthalmology • Retinal Vein Occlusion

Intraocular Pressure Outcomes Following Suprachoroidal Triamcinolone Acetonide in Patients With Glaucoma, Ocular Hypertension, or Steroid Response. (PubMed, J Vitreoretin Dis) - "In this population, there was a lower tendency to have an IOP response following suprachoroidal triamcinolone acetonide compared with published rates of IOP elevation from intraocular steroids in eyes without a known steroid response. All patients receiving local corticosteroids should be monitored for IOP elevations."

Journal • Cardiovascular • Glaucoma • Ocular Inflammation • Ophthalmology • Uveitis

Secondary Macular Hole Closure With Sub-Tenon Triamcinolone Acetonide. (PubMed, J Vitreoretin Dis) - "No recurrence was observed at follow-up. Sub-Tenon triamcinolone acetonide is a promising therapeutic option for the management of secondary macular holes less than 200 µm in diameter, demonstrating efficacy in promoting hole closure and improving visual outcomes."

Journal • Macular Edema • Ophthalmology • Retinal Disorders

An Unusual Complication of Intralesional Corticosteroid Injections: Two Case Reports. (PubMed, Curr Rheumatol Rev) - "Clinicians should be aware of this potential side effect when administering corticosteroid injections and inform patients accordingly. While hypopigmentation is typically self-limiting, patient education and reassurance are essential, particularly for individuals with darker skin types."

Journal • Inflammation • Musculoskeletal Diseases

Vulvar Crohn disease: A case report. (PubMed, SAGE Open Med Case Rep) - "She was experiencing painful vulvar fissures, which ultimately resulted in a diagnosis of vulvar Crohn's disease. The patient's symptoms had resolved at the most recent follow-up visit with treatment, including adalimumab 40 mg, metronidazole 500 mg, and intralesional triamcinolone acetonide injections."

Journal • Crohn's disease • Dermatology • Gastroenterology • Genetic Disorders • Hidradenitis Suppurativa • Immunology • Inflammatory Bowel Disease • Pain • Psoriasis

Effectiveness and Safety of Intravitreal Brolucizumab for Diabetic Macular Edema After Vitrectomy: A Before-and-After Study at a Specialized Center in Japan. (PubMed, Clin Ophthalmol) - "If CST did not improve after the last IVBr injection, treatment was switched to intravitreal triamcinolone acetonide injection (IVTA), sub-Tenon's triamcinolone acetonide (STTA) injection, or intravitreal faricimab (IVFa)...Our findings demonstrated partial efficacy of IVBr in managing DME in vitrectomized eyes. However, variable responses often necessitate supplementary treatments to achieve therapeutic goals."

Journal • Diabetes • Diabetic Macular Edema • Inflammation • Metabolic Disorders • Ophthalmology

DVS: Dropless Pars Plana Vitrectomy Study (clinicaltrials.gov) - P4 | N=168 | Recruiting | Sponsor: Massachusetts Eye and Ear Infirmary | Trial completion date: Jan 2026 ➔ Jan 2027 | Trial primary completion date: Jul 2025 ➔ Jul 2026

Trial completion date • Trial primary completion date • Retinal Disorders

Punch Excision Therapy for the Treatment of Keloids: A Systematic Review (CDA 2025) - "Moreover, one case series study (n=30) reported a 69.6% decrease in Patient and Observer Scar Assessment Scale (POSAS) 2.0 scores after punch excision therapy combined with triamcinolone acetonide injection... Punch excision therapy shows promising efficacy for keloid improvement, being cost-effective and accessible. However, further comparative studies with standardized treatment protocols, measurement tools, and long-term follow-up are needed to fully understand its benefits and role in the comprehensive management of keloids."

Review • Fibrosis • Pain • IL6 • TGFB1

Esophageal stricture due to corrosive substance ingested and delayed management: A case report. (PubMed, Trauma Case Rep) - "Despite 14 times of endoscopic performed combined with dilation and Triamcinolone Acetonide injection, the esophageal and pyloric strictures recurrence occurred several times...Local steroids are less likely to cause challenges during esophageal dilatation than systemic or oral steroids. Corrosive substance ingestion negatively impacts the upper gastrointestinal system; one of the case is esophageal stricture, which requires lengthy management of lumen narrowing recurrence."

Journal

An Effective Auricular Keloids Management Method: Excision of the Original Lesion and Postoperative Corticosteroids. (PubMed, Aesthetic Plast Surg) - "For keloids with diverse morphologies and anatomic locations, adopting individualized combined treatment involving surgical excision and intralesional triamcinolone acetonide injections can achieve the reconstruction of auricle morphology and maintain a long-term therapeutic effect."

Journal • Fibrosis

Formulation, in-vitro characterization and clinical evaluation of curcumin in-situ gel for treatment of oral submucosal fibrosis (OSF). (PubMed, Int J Pharm) - P=N/A | "This study demonstrates that curcumin thermosensitive in-situ gels, as a novel dosing regimen, can achieve painless management of OSF, which is also the novelty of this work."

Journal • Preclinical • Fibrosis • Gastrointestinal Disorder • Immunology • Oncology • Pain

Elucidating medication waste for outpatient clinic procedures with intralesional triamcinolone (SID 2025) - "We conducted a retrospective chart review for patients receiving intralesional steroid injections with Kenalog-40 or Kenalog-10 at our academic institution from 01/01/2020–12/31/2023 for the treatment of scars, keloids, or different types of alopecia. Our results highlight an urgent opportunity to reduce unnecessary medical waste from single-use medications and the importance of considering how our daily practice affects our environmental impact. Encouraging sustainable practices such as optimizing medication dosing and preparation, implementing a return program for unused medication, and increasing awareness may help minimize medical waste in dermatology."

Clinical • Alopecia • Dermatology • Fibrosis • Immunology

Combining orbital intensity modulated radiation therapy with periorbital triamcinolone acetonide injection for Graves' orbitopathy. (PubMed, Int J Ophthalmol) - "The combination therapy demonstrates significant effectiveness in treating patients with GO who experienced severe ocular inflammation and have previous GPT failure. Noticeable improvement is observed as early as one month after initiating radiation therapy, and patients with more severe inflammatory states showes greater benefit from the treatment."

Journal • Inflammation • Ocular Inflammation • Ophthalmology • Thyroid Eye Disease

A case of retinal phlebitis complicated by punctate inner choroidopathy-like lesion (ARVO 2025) - "The patient was started on oral prednisolone (PSL) therapy...Layman Abstract (optional): Provide a 50-200 word description of your work that non-scientists can understand. Describe the big picture and the implications of your findings, not the study itself and the associated details."

Clinical • Ocular Inflammation • Ophthalmology

Recurrent uveitic macular edema managed with intravitreal faricimab injection. (PubMed, J Ophthalmic Inflamm Infect) - "The findings of this case hint towards the potential simultaneous effect of angiopoietin-2 blockade along with vascular endothelia growth factor A inhibition by faricimab in managing treatment-resistant UME. Nonetheless, more studies focusing on the role of intravitreal faricimab in UME are required."

Journal • Macular Edema • Ocular Inflammation • Ophthalmology • Retinal Disorders • Vasculitis

Efficacy of Combined 595-nm Pulsed Dye Laser and Intralesional Corticosteroids Versus Intralesional Corticosteroids Alone for Treating Postmastectomy Hypertrophic Scars and Keloids in Transgender Men: A Randomized Controlled Trial. (PubMed, J Cosmet Dermatol) - "The addition of 595-nm PDL to IL TAC may provide more favorable outcomes for treating postmastectomy HTS and keloids among TM."

Clinical • Journal • Fibrosis