IMD-4482 / Institute of Medicinal Molecular Design - LARVOL DELTA

The Role of Plasminogen Activator Inhibitor-1 in Uveitis: Findings from Clinical and Experimental Studies. (PubMed, Curr Eye Res) - "The severity of EAU treated with the PAI-1 inhibitor; IMD4482, was clinically assessed over time...Our findings indicate that the level of PAI-1 is locally high in the eye of uveitis patients as well as in experimental uveitis models. Suppression of EAU through PAI-1 inhibition highlights its potential as a therapeutic target for uveitis."

Journal • Genetic Disorders • Immunology • Inflammation • Ocular Inflammation • Ophthalmology • Retinal Disorders • Uveitis