CD4 co-receptor inhibitor / Theriva Bio - LARVOL DELTA

HLA-E/peptide complexes differentially interact with NKG2A/CD94 and T cell receptors. (PubMed, J Immunol) - "The Arginine at position 5 of these peptides is an essential residue for recognition by both receptors. Thus, NKG2A/CD94 and TCRs have different requirements for recognition of peptides presented in HLA-E."

Journal • Cytomegalovirus Infection • HLA-E • KLRC1 • KLRD1