vernakalant oral / Merck (MSD), Correvio - LARVOL DELTA

Pharmacologic Cardioversion in Patients with Paroxysmal Atrial Fibrillation: A Network Meta-Analysis. (PubMed, Cardiovasc Drugs Ther) - "Our network meta-analysis identified with sufficient power and consistency the most effective antiarrhythmics for pharmacologic cardioversion over different time settings, with vernakalant and flecainide exhibiting a safer and more efficacious profile toward faster cardioversion."

Journal • Retrospective data • Review • Atrial Fibrillation • Cardiovascular

Pharmacologic cardioversion of recent-onset atrial fibrillation: a systematic review and network meta-analysis. (PubMed, Europace) - "For pharmacologic cardioversion of recent-onset AF within 24 h, there is insufficient evidence to determine which treatment is superior. Vernakalant and flecainide may be relatively more efficacious agents. Propafenone and IV amiodarone may be relatively less efficacious. Further high-quality study is necessary."

Journal • Retrospective data • Review