Undisclosed MSC-derived Exosomes with KrasG12D siRNA / UT MD Anderson Cancer Center - LARVOL DELTA

iEXPLORE: iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation (clinicaltrials.gov) - P1/2 | N=28 | Recruiting | Sponsor: M.D. Anderson Cancer Center | Phase classification: P1 ➔ P1/2

Phase classification • Oncology • Pancreatic Cancer • Pancreatic Ductal Adenocarcinoma • Solid Tumor • KRAS

iEXPLORE: iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation (clinicaltrials.gov) - P1 | N=28 | Recruiting | Sponsor: M.D. Anderson Cancer Center | Active, not recruiting ➔ Recruiting | N=15 ➔ 28

Enrollment change • Enrollment open • Oncology • Pancreatic Cancer • Pancreatic Ductal Adenocarcinoma • Solid Tumor • KRAS

iEXPLORE: iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation (clinicaltrials.gov) - P1 | N=15 | Active, not recruiting | Sponsor: M.D. Anderson Cancer Center | Trial completion date: Apr 2025 ➔ Apr 2027 | Trial primary completion date: Apr 2025 ➔ Apr 2027

Trial completion date • Trial primary completion date • Hepatology • Oncology • Pancreatic Cancer • Pancreatic Ductal Adenocarcinoma • Solid Tumor • KRAS

NCI-2018-01441: iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation (clinicaltrials.gov) - P1 | N=15 | Active, not recruiting | Sponsor: M.D. Anderson Cancer Center | Recruiting ➔ Active, not recruiting | N=28 ➔ 15 | Trial completion date: Jun 2023 ➔ Apr 2025 | Trial primary completion date: Jun 2023 ➔ Apr 2025

Enrollment change • Enrollment closed • Metastases • Stroma • Trial completion date • Trial primary completion date • Gastrointestinal Cancer • Hepatology • Oncology • Pancreatic Cancer • Pancreatic Ductal Adenocarcinoma • Solid Tumor • KRAS

NCI-2018-01441: iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation (clinicaltrials.gov) - P1 | N=28 | Recruiting | Sponsor: M.D. Anderson Cancer Center | Trial completion date: Mar 2023 ➔ Jun 2023 | Trial primary completion date: Mar 2023 ➔ Jun 2023

Metastases • Stroma • Trial completion date • Trial primary completion date • Gastrointestinal Cancer • Hepatology • Oncology • Pancreatic Cancer • Pancreatic Ductal Adenocarcinoma • Solid Tumor • KRAS