TAK-021 / Takeda - LARVOL DELTA

TAK - 021, an inactivated Enterovirus 71 vaccine candidate, provides cross-protection against heterologous sub-genogroups in human scavenger receptor B2 transgenic mice. (PubMed, Vaccine) - "The results show that TAK-021 can confer protection in mice against the EV71 sub-genogroups tested."

Journal • Preclinical

An inactivated enterovirus 71 vaccine is safe and immunogenic in healthy adults: A phase I, double blind, randomized, placebo-controlled, study of two dosages. (PubMed, Vaccine) - "These data show that the EV71 candidate vaccine is safe and immunogenic in adults and supports further clinical development as a potential pediatric vaccine by initiating a dose-escalation study for determining the dose-dependent safety and immunogenicity of the vaccine in young naïve children."

Clinical • Journal • Pain • Pediatrics