ProLindac (AP 5346) / Abeona Therap - LARVOL DELTA

Acid-sensitive prodrugs; a promising approach for site-specific and targeted drug release. (PubMed, Eur J Med Chem) - "These prodrugs include albumin-binding prodrugs (Aldoxorubicin and DK049), polymeric micelle (NC-6300), polymer conjugates (ProLindac™), and an immunoconjugate (IMMU-110). The article encompasses a broad spectrum of studies focused on the development of acid-sensitive prodrugs for anticancer, antibacterial, and anti-inflammatory agents. Finally, the challenges associated with the acid-sensitive prodrug strategy are discussed, along with future directions."

Journal • Review • Infectious Disease • Oncology