SC-007 / AbbVie - LARVOL DELTA

Broad-spectrum synthetic carbohydrate receptors (SCRs) inhibit viral entry across multiple virus families. (PubMed, Sci Adv) - "Notably, SCR005 and SCR007, which exhibited minimal toxicity, significantly reduced SARS-CoV-2 infection in a severe animal model with a single dose. Mechanistic studies suggested that SCRs bind viral envelope N-glycans, blocking viral attachment and/or fusion. These results identify conserved viral N-glycans as promising BSA targets and establish SCRs as candidate prophylactic agents against enveloped viruses with pandemic potential."

Journal • Infectious Disease • Novel Coronavirus Disease • Respiratory Diseases