MAG200 / Magellan Biologicals - LARVOL DELTA

NEXCELL-OAK: A Study to Investigate the Effectiveness, Safety, and Tolerability of MAG200 Solution for Intra-articular Injection Compared With Placebo in Participants Aged 35 to 75 Years of Age With Symptomatic Osteoarthritis of the Knee. (clinicaltrials.gov) - P3 | N=573 | Not yet recruiting | Sponsor: Magellan Stem Cells

New P3 trial • Immunology • Osteoarthritis • Pain • Rheumatology

Organo magadiites for diclofenac adsorption: influence of the surfactant chain. (PubMed, Environ Sci Pollut Res Int) - "Diclofenac removal by samples was not affected by the presence of ibuprofen, which was also removed from binary system by organophilic magadiites reaching removal of 76.5% and 86.9% by C16pyMag100% and C16pyMag200%, respectively. Regeneration studies demonstrated a drug removal percentage of 83-92% for C16pyMag and C16Mag after three cycles of adsorption."

Journal

Safety and efficacy of an allogeneic adipose-derived mesenchymal stem cell preparation in the treatment of knee osteoarthritis: A Phase I/IIa randomised controlled trial. (PubMed, Osteoarthr Cartil Open) - "This early-phase study provides supportive safety and efficacy evidence to progress MAG200 to later-stage trial development. ACTRN12617001095358/ACTRN12621000622808."

Journal • P1/2 data • Immunology • Osteoarthritis • Pain • Rheumatology