mometasone furoate / Generic mfg. - LARVOL DELTA

CD21 Things can only get redder! Two cases of allergic contact dermatitis to topical brimonidine tartrate gel. (PubMed, Br J Dermatol) - "Allergic contact blepharitis to brimonidine eye drops is recognized and, more recently, case reports have described patients developing ACD to topical brimonidine gel [Bangsgaard N, Fischer LAN, Zachariae C. Sensitization to and allergic contact dermatitis caused by Mirvaso® (brimonidine tartrate) for treatment of rosacea - 2 cases...He had been using topical Elocon cream daily (mometasone furoate 0.1%) and was diagnosed with steroid-induced rosacea. He was prescribed oral doxycycline, ivermectin cream and brimonidine gel...We would like to raise awareness that in addition to rebound erythema, topical brimonidine gel is also a cause of severe facial ACD. Patch testing to the patient's own medicaments should be performed in suspected cases."

Journal • Allergy • Contact Dermatitis • Dermatitis • Dermatology • Dry Eye Disease • Immunology • Ocular Inflammation • Ophthalmology • Rosacea • CD21

CD09 Complexities of contact dermatitis: lessons from a case of concomitant budesonide and propylene glycol sensitivity. (PubMed, Br J Dermatol) - "Positive reactions on day 4 included propylene glycol 20%, colophony 20%, jasmine absolute Egyptian, tixocortol-21-pivalate 1% in petrolatum, budesonide 0.01% in petrolatum and mometasone furoate ointment...Safe alternatives were recommended, while propylene glycol-containing products such as Dermovate, Metosyn and Synalar were to be avoided...Contact Dermatitis 2019; 81: 280-7). Vigilant allergen avoidance, individualized treatment plans and education are paramount for optimal management to prevent exposure to such allergens in future treatments."

Journal • Allergy • Contact Dermatitis • Dermatitis • Dermatology • Immunology

PA28 Cutaneous sarcoidosis mimicking molluscum contagiosum. (PubMed, Br J Dermatol) - "In July 2023, dupilumab was commenced by the respiratory team for her severe asthma and it had a beneficial effect on her eczema...Lymecycline 408 mg once daily for 2 months and mometasone furoate 0.1% ointment were commenced but the disease continued to progress. We then commenced doxycycline 100 mg daily alongside mometasone furoate 0.1% ointment due to the patient's strong desire to avoid blood tests...Although it is an uncommon presentation, it is important to be aware of it as a differential diagnosis in cases of atypical molluscum contagiosum. This case, in addition to its severity and rarity, has proven challenging to manage given the patient's severe venepuncture phobia."

Journal • Asthma • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Ophthalmology • Pediatrics • Pulmonary Disease • Respiratory Diseases • Sarcoidosis

Impact of Intraocular Lens Design on Refractive Endpoint Selection: A Call for a New Paradigm. (PubMed, Clin Ophthalmol) - "The evidence suggests that a universal refractive target (eg, plano) may be suboptimal for many advanced IOLs and that customized refractive planning-often incorporating mini-monovision or asymmetrical targets-can improve visual outcomes. Future research should aim to standardize defocus measurement techniques and refine classification systems to better guide clinical decision-making."

Journal • Review • Cataract • Ophthalmology

Acupuncture for chronic eczema of blood deficiency stirring wind: a randomized controlled trial (PubMed, Zhongguo Zhen Jiu) - "The control group was treated with mometasone furoate cream, once a day for the first 2 weeks, twice a week for the subsequent 2 weeks...In follow-up, the difference in recurrence rates between the two groups was not statistically significant (P>0.05). Acupuncture can improve the clinical symptoms, TCM syndrome, quality of life of CE patients with blood deficiency stirring wind."

Clinical • Journal • Atopic Dermatitis • Dermatology • Immunology

Adjuvant therapy of severe and/or refractory bullous pemphigoid with immunoadsorption - A prospective monocenter pilot study. (PubMed, J Dtsch Dermatol Ges) - "IA can be considered as a relatively safe and effective adjuvant therapy for patients with severe or refractory BP."

Journal • Bullous Pemphigoid • Dermatology • Dermatopathology • Immunology

Skin Eczema Limited to Transplanted Hand. (PubMed, Clin Cosmet Investig Dermatol) - "Topical mometasone furoate ointment combined with an increased dose of oral prednisone (from 5 mg/day to 10 mg/day) resulted in marked improvement within two weeks, followed by complete resolution after several weeks of regular emollient use. Because eczema can closely mimic rejection, it may complicate post-transplant care and lead to unnecessary changes in immunosuppressive therapy if misdiagnosed. Accurate diagnosis is essential for appropriate management and graft survival."

Journal • Atopic Dermatitis • Contact Dermatitis • Dermatology • Immunology • Transplant Rejection • Transplantation

Efficacy and Safety of Runzaozhiyang Lotion for Chronic Hand Eczema: Protocol for a Randomized Controlled Trial. (PubMed, JMIR Res Protoc) - "Participants in the intervention group will receive RZZYL granules along with a placebo cream of mometasone furoate, whereas the control group will get mometasone furoate cream in combination with a placebo for RZZYL granule...This protocol addresses the limitations of previous research and aims to explore the efficacy and safety of RZZYL in treating CHE through a higher-quality clinical study. It seeks to provide additional treatment options for patients with CHE who are resistant to or have poor responses to current therapies."

Clinical • Clinical protocol • Journal • Atopic Dermatitis • Contact Dermatitis • Dermatology • Immunology • Inflammation • Pruritus

A rare case of infantile gluteal granuloma and tinea incognita in a toddler: diagnostic pitfalls and clinical relevance (EADV 2025) - "The lesion worsened after unsupervised topical use of mometasone furoate and fusidic acid... This case reinforces the importance of early clinical recognition and fungal investigation in persistent inflammatory lesions in infants, especially those previously exposed to topical corticosteroids. It contributes meaningful insight to the limited national literature on IGG and underscores the diagnostic complexity introduced by tinea incognita. The case advocates greater clinical awareness within the fields of pediatric dermatology and clinical mycology."

Clinical • Atopic Dermatitis • Candidiasis • Contact Dermatitis • Dermatitis • Dermatology • Immunology • Infectious Disease • Pediatrics

napkin psoriasis: misdiagnosed as diaper dermatitis, leading to delayed treatment (EADV 2025) - "Based on clinical and histopathological findings, the patient was diagnosed with napkin psoriasis, and was treated with a mixture of petroleum jelly and mometasone furoate cream 0.1% for two weeks, and pure hydrocortisone 0.1% cream was applied to the face, axillary, and genital areas... This case highlights the importance of considering psoriasis in the differential diagnosis of persistent or treatment- resistant diaper rash, especially when lesions extend beyond the diaper area. Early dermatological assessment and appropriate treatment can lead to rapid and effective disease control, even in infancy. This case also highlights the need for high awareness and timely intervention in pediatric dermatology to ensure optimal patient outcomes."

Atopic Dermatitis • Contact Dermatitis • Dermatitis • Dermatology • Immunology • Pediatrics • Psoriasis

Trichophyton indotineae dermatophytosis in a patient with Familiar Mediterranean Fever: what a (therapeutic) journey (EADV 2025) - "The eruption started approximately 7 months before presentation on his groins and thighs and was initially treated with an over-the-counter cream containing miconazole and hydrocortisone. The lesions continued to spread, and therefore the patient contacted his general practitioner who, following a positive PCR for T. interdigitale, initiated treatment with oral terbinafine at a dose of 250 mg daily and topical mometasone furoate cream...After consulting with the rheumatologist, colchicine treatment was interrupted and oral itraconazole 200 mg daily was initiated, resulting in partial improvement after 4 weeks of treatment...The patient was put on anakinra treatment by the rheumatologist and itraconazole treatment was extended to 3 months as a new culture revealed preserved sensitivity to itraconazole... In terbinafine-resistant dermatophytosis, the challenges seem to go beyond difficulties in species identification, susceptibility testing and identifying clinical..."

Clinical • Dermatology • Rheumatology

Clinical Spectrum of Demodicosis Among Filipinos with Brown Skin: A Case Series (EADV 2025) - "Patient used unregulated lightening products containing tretinoin, hydroquinone 2% and clobetasol 0.05% cream for 6 years with minimal improvement. Clinical and histopathological diagnosis revealed rosacea, dyschromia with demodicosis and patient was prescribed low dose isotretinoin and ivermectin 1% cream for the demodex infestation...Another consult done, diagnosed as eczema and was prescribed mometasone furoate 0.1% cream and anti-acne medications with no improvement... Demodicosis is a common skin condition with varying clinical features often underdiagnosed or mistaken for other dermatoses. This case series has documented four cases of demodicosis in patients with diverse clinical manifestations, predisposing factors and therapeutic responses. These findings underscore the importance of early clinical recognition, adequate laboratory investigation and individualized treatment approaches to achieve favorable outcomes."

Clinical • Acne Vulgaris • Atopic Dermatitis • Dermatitis • Dermatology • Dermatopathology • Immunology • Rosacea

Coexistence of Williams Syndrome and Atopic Dermatitis: A Rare Case and Clinical Implications (EADV 2025) - "The patient was started on a treatment regimen consisting of topical mometasone furoate oinment, systemic prednisolone (32 mg/d), and regular emollient therapy... The coexistence of Williams syndrome and atopic dermatitis is a rare clinical occurrence, warranting further studies to elucidate potential shared pathophysiological mechanisms. Multidisciplinary assessment of such cases may contribute to the development of individualized treatment strategies, optimizing patient management."

Clinical • Atopic Dermatitis • Cardiovascular • Cognitive Disorders • Dermatitis • Dermatology • Developmental Disorders • Genetic Disorders • Immunology • Primary Immunodeficiency • Psychiatry

Lichen myxedematosus associated with HIV and hepatitis B (EADV 2025) - "The patient started topical mometasone furoate for symptomatic relief and was referred to the Infectious Diseases Department, where antiretroviral therapy with TAF/FTC was initiated. Due to the rarity of this condition, there is no standardized therapeutic consensus. Various treatment options have been described with variable efficacy, including topical corticosteroids, calcineurin inhibitors, and systemic agents such as isotretinoin. In this particular case, therapeutic options were limited given the presence of multiple active infections."

Dermatology • Hematological Disorders • Hepatitis B • Hepatitis C • Hepatology • Human Immunodeficiency Virus • Infectious Disease • Inflammation • Mood Disorders • Neutropenia

Reflectance Microscopic changes of Vulvar Lichen Sclerosus after 5-Aminolevulinic Acid Photodynamic Therapy (ChiCTR) - P=N/A | N=80 | Recruiting | Sponsor: Weifang People's Hospital; Weifang People's Hospital

New trial • Dermatology

Unilateral Osteonecrosis of the Femoral Head in a Patient with Atopic Dermatitis Due to Uncontrolled Topical Steroid Treatment, a Case Report. (PubMed, Reports (MDPI)) - "The patient reported the prolonged uncontrolled use of topical mometasone furoate for five years due to AD. Following the diagnosis, topical corticosteroids were discontinued, and the treatment was shifted to tacrolimus and, subsequently, to oral methotrexate with folic acid...It underscores the importance of monitoring systemic side effects in dermatological therapies and educating patients on proper corticosteroid use. Alternative treatments, such as upadacitinib, should be considered in young male patients to prevent severe complications."

Journal • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Orthopedics • Pain

When Normal Flora Turns Pathogenic: A Pediatric Case of Infectious Eczematoid Dermatitis. (PubMed, Cureus) - "The lesions were initially treated with topical fluocinolone acetonide prescribed by an otolaryngologist, without clinical improvement...The patient was treated with ciprofloxacin, selected based on antibiotic sensitivity, along with mometasone furoate 0.1% cream to address both infectious and inflammatory components. On follow-up, the lesions showed improvement; however, the patient was later lost to follow-up. This case highlights the need to consider IED in children with refractory eczematous eruptions."

Journal • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Infectious Disease • Otorhinolaryngology • Pediatrics

0.005% Latanoprost Gel for Nonsegmental Vitiligo (clinicaltrials.gov) - P2 | N=10 | Not yet recruiting | Sponsor: Universitas Padjadjaran

New P2 trial • Dermatology • Immunology • Vitiligo

Secondary Cicatricial Scalp Alopecia Caused by Brunsting-Perry Pemphigoid: A Case Report. (PubMed, Cureus) - "Intralesional betamethasone was successful in the treatment, and topical mometasone furoate lotion was used to maintain the result. Our case suggests that Brunsting-Perry pemphigoid may be underdiagnosed as the reason for scarring alopecia, considering the scarce information about the disease in the literature."

Journal • Alopecia • Bullous Pemphigoid • Dermatology • Immunology • Inflammation

Randomized controlled study of mometasone furoate and tacrolimus in the treatment of vulvar lichen sclerosus (ChiCTR) - P=N/A | N=120 | Recruiting | Sponsor: Obstetrics and Gynecology Hospital of Fudan University; Obstetrics and Gynecology Hospital of Fudan University

New trial • Dermatology

Efficacy of natural weak acid repair cream in the treatment of infantile atopic dermatitis and its effect on microecology (ChiCTR) - P4 | N=350 | Not yet recruiting | Sponsor: The First Affiliated Hospital,Sun Yat-sen University; The First Affiliated Hospital,Sun Yat-sen University

New P4 trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Lichen Planus Pigmentosus as a Cutaneous Extrahepatic Manifestation of Chronic Hepatitis C Virus Infection: A Case Report. (PubMed, Int Med Case Rep J) - "The patient was treated with sun avoidance and photoprotection, mometasone furoate 0.1% cream twice a day, and direct-acting antiviral agents. Improvement was observed clinically and supported by spectrophotometry examination. This case highlights lichen planus pigmentosus as a potential indicator of previously undetected hepatitis C virus infection, recommending hepatitis C virus testing for patients with lichen planus pigmentosus."

Journal • Dermatitis • Dermatology • Dermatopathology • Fibrosis • Gastroenterology • Hepatitis C • Hepatology • Immunology • Infectious Disease • Inflammation • Lichen Planus • Liver Cirrhosis

Different Modalities in the Management of Post-COVID-19 Olfactory Dysfunction. (PubMed, Indian J Otolaryngol Head Neck Surg) - "A combination of topical mometasone furoate, vitamin A, or intranasal theophylline with olfactory training can shorten post-COVID-19 olfactory dysfunction. However, no significant smell score improvement was found when compared to olfactory training alone after four weeks. Diabetes, hypertension, smoking, and asthma adversely affect complete smell recovery within four weeks of treatment."

Journal • Asthma • Cardiovascular • Diabetes • Genetic Disorders • Hypertension • Immunology • Infectious Disease • Metabolic Disorders • Novel Coronavirus Disease • Obesity • Pulmonary Disease • Respiratory Diseases

Efficacy and Safety of Proactive Therapy with 2% Crisaborole Ointment in Children with Mild-to-Moderate Atopic Dermatitis: A Randomized Controlled Study. (PubMed, Paediatr Drugs) - P=N/A | "Proactive treatment with crisaborole ointment for children older than 2 years with mild-to-moderate AD effectively reduces flare-ups and reliance on topical corticosteroids, demonstrating good tolerability and safety."

Journal • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Clinical observation of sequential topical Mometasone Furoate Cream versus Tapinarof in the treatment of atopic dermatitis in adults (ChiCTR) - P4 | N=60 | Sponsor: Xiangya Hospital of Central South University; CHINA ASSOCIATION OF MEDICAL EQUIPMENT

New P4 trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology