mometasone furoate / Generic mfg. - LARVOL DELTA

Population-Level Burden of Dermatitis and the Effects of Moxibustion and Capsaicin on Pruritus and JAK/STAT Signaling in Atopic Dermatitis: A Multilevel Study. (PubMed, Mediators Inflamm) - "Aggregated dermatitis continues to impose a substantial and unevenly distributed global health burden. Within this broader public-health context, the experimental findings indicate that moxibustion and topical capsaicin alleviate pruritus and inflammatory skin damage in rats with AD. These improvements were accompanied by attenuation of IFN-γ/JAK1/STAT1/STAT3-associated signaling, supporting the potential involvement of the JAK/STAT pathway in the observed treatment responses."

Journal • Review • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Pruritus • IFNG • IL10 • IL4 • IL6 • JAK1 • STAT1 • TNFA • TRPV1

Patient‑Reported Outcomes in Paediatric Atopic Dermatitis Treated with Mometasone Furoate 0.1% Cream (EADV 2026) - No abstract available

Clinical • Patient reported outcomes • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Pediatrics

Successful Management and Treatment Rechallenge Following Docetaxel-Induced Serpentine Supravenous Hyperpigmentation With Bullous Features: A Case Report. (PubMed, Clin Case Rep) - "We report the case of a 50-year-old woman with HER2-positive breast cancer who developed bullous SSH 5 days after her first cycle of TCHP (docetaxel, carboplatin, trastuzumab, pertuzumab) chemotherapy. The patient completed all six planned cycles and subsequently achieved pathologic complete response. This case is the first to demonstrate that conservative management of bullous SSH with topical mometasone furoate, combined with contralateral venous access and thorough saline flushing, enables successful rechallenge and uninterrupted continuation of planned oncological treatment with pathologic complete response as the outcome."

Journal • Breast Cancer • HER2 Breast Cancer • HER2 Positive Breast Cancer • Oncology • Solid Tumor • HER-2

A randomized assessor-blinded triple-arm pilot study to compare the efficacy of mometasone furoate 0.1% ointment versus crisaborole 2% ointment versus tofacitinib 2% ointment twice daily in patients with mild to moderate atopic dermatitis. (PubMed, J Am Acad Dermatol) - No abstract available

Journal • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

A randomized controlled clinical trial of transfer factor oral solution in the treatment of atopic dermatitis (ChiCTR) - P4 | N=160 | Recruiting | Sponsor: Southern Medical University Dermatology Hospital; Dematology Hospital of Southern Medical University

New P4 trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Trastuzumab Deruxtecan-Associated Vitiligo Treated with Topical Janus Kinase Inhibitor in Human Epidermal Growth Factor Receptor 2-Low Metastatic Breast Cancer: A Case Report (EADV-Sp 2026) - "She was initially treated with topical mometasone furoate cream, without improvement...Topical calcineurin inhibitor therapy with ointment tacrolimus 0.03% was added twice weekly but proved ineffective...The response to topical ruxolitinib indicates a JAK-STAT–mediated mechanism. Early dermatologic intervention may help manage this rare adverse effect and allow continuation of anticancer therapy. Further reports are needed to clarify its pathophysiology"

Case report • Clinical • Metastases • Alopecia • Breast Cancer • Dermatology • Estrogen Receptor Positive Breast Cancer • HER2 Breast Cancer • HER2 Positive Breast Cancer • Hormone Receptor Breast Cancer • Hormone Receptor Positive Breast Cancer • Immunology • Interstitial Lung Disease • Oncology • Pulmonary Disease • Respiratory Diseases • Solid Tumor • Vitiligo • ER • HER-2 • IFNG

Paradoxical Immune Reactions under IL-17 Blockade: Insights from a Clinical Case Series (EADV-Sp 2026) - "Topical treatment with mometasone furoate ointment and keratolytic agents was initiated...Case 2: A 50-year-old female patient with a history of psoriatic arthritis (PsA) since 2021 and PV since 2022 was switched to ixekizumab in December 2022 after methotrexate (MTX) and apremilast proved ineffective...Topical treatment with calcipotriol and betamethasone dipropionate foam was prescribed, leading to a favorable clinical response...However, worsening of PV prompted a switch to adalimumab in August 2023, followed by a further switch to risankizumab in October 2024 due to fluctuating disease activity. Case 4: A 56-year-old woman with palmoplantar PV and autoimmune thyroiditis was started on ixekizumab in November 2025 after failure of MTX and topical therapies (betamethasone+calcipotriol and tazarotene)...Ixekizumab was discontinued, and treatment with topical steroids and systemic colchicine was initiated, resulting in marked improvement within two months...Conclusions..."

Clinical • Endocrine Disorders • Immunology • Inflammatory Arthritis • Plaque Psoriasis • Psoriasis • Psoriatic Arthritis • Pustular Psoriasis • Seronegative Spondyloarthropathies

A randomized assessor-blinded triple arm pilot study to compare the efficacy of mometasone furoate 0.1% ointment versus crisaborole 2% ointment versus tofacitinib 2% ointment twice daily in patients with mild to moderate atopic dermatitis. (EADV-Sp 2026) - "Conclusions Topical tofacitinib 2% and mometasone 0.1% are highly effective and well-tolerated for mild-to-moderate AD, whereas crisaborole shows moderate benefit. Tofacitinib and crisaborole offers a promising steroid-sparing therapeutic alternative."

Clinical • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Pruritus

Paradoxical Alopecia Areata Linked to Adalimumab-atto: case series (EADV-Sp 2026) - "Adalimumab-atto was discontinued, and topical clobetasol propionate 0.05% ointment was initiated...His disease was refractory to oral corticosteroids, cyclosporine, and acitretin but achieved control for 43 weeks with ustekinumab, which was discontinued due to financial constraints...Adalimumab-atto was continued with close monitoring, cyclosporine was tapered and discontinued, and topical therapy for alopecia with alternating mometasone furoate lotion and tacrolimus 0.1% ointment was started...Examination of the palms reveals diffuse, symmetric, yellow-orange waxy hyperkeratosis with accentuated skin markings, consistent with palmoplantar involvement of pityriasis rubra pilaris, and the trunk and neck demonstrate controlled pityriasis rubra pilaris at the time of alopecia onset. Results N/A Conclusions - Borderline paradoxical alopecia areata is a rare but clinically significant immune-mediated adverse effect of TNF-α inhibitors, including the biosimilar adalimumab-atto..."

Clinical • Alopecia • Endocrine Disorders • Hematological Disorders • Immune Thrombocytopenic Purpura • Immunology • Inflammatory Arthritis • Plaque Psoriasis • Psoriasis • Psoriatic Arthritis • Seronegative Spondyloarthropathies • Thrombocytopenia • Thrombocytopenic Purpura • Vitiligo

Subcorneal pustular dermatosis: expanding the spectrum of dupilumab-associated cutaneous adverse effects (EADV-Sp 2026) - "Notably, a few weeks after initiation, he developed a cutaneous eruption diagnosed as acute generalized exanthematous pustulosis (AGEP) possibly related to trimetoprim/sulfamethoxazole...Although he had achieved mild relief with mometasone furoate cream, frequent flare- ups of annular cutaneous lesions occurred...Owing to the excellent respiratory response to dupilumab and acceptable control of the pruritus and the lesions with mometasone cream and tacrolimus ointment, it was decided to maintain dupilumab and topical treatment as required...Another case of SPD successfully treated with abrocitinib was reported in a patient in whom dupilumab was started to treat suspected atopic dermatitis, although the nature of the rash might have been misdiagnosed...These results suggest SPD may be a rare cAEs of dupilumab therapy, widely used for cutaneous and noncutaneous inflammatory diseases. Our case highlights the need of a low threshold for biopsy when facing pustular and/or..."

Adverse events • Atopic Dermatitis • Cardiovascular • Chronic Obstructive Pulmonary Disease • Dermatitis • Dermatology • Hematological Disorders • Immunology • Pruritus • Psoriasis • Pulmonary Disease • Respiratory Diseases • Thrombosis • IL13 • IL4

Annular leukocytoclastic vasculitis associated with isolated anti-β2 glycoprotein I immunoglobulin G positivity: A case report. (PubMed, SAGE Open Med Case Rep) - "He was managed with oral prednisolone 40 mg daily as a tapered dosage regimen, in combination with topical mometasone furoate 0.1% cream applied twice daily, resulting in complete resolution of lesions. To the best of our knowledge, this is the first reported case of annular morphology of leukocytoclastic vasculitis with microvascular occlusions in the Middle East."

Journal • Dermatology • Genetic Disorders • Hematological Disorders • Inflammation • Vasculitis

MASCC clinical practice statement: Prevention and management of acute radiation dermatitis using topical corticosteroids. (PubMed, Support Care Cancer) - "TCs are recommended for the prevention of ARD in selected patients with head and neck and breast cancers at a high risk of ARD. TC is also a treatment option for the management of patients with early ARD without evidence of moist desquamation. Medium potency TCs, such as mometasone furoate 0.1% cream, are preferred. Healthcare professionals should monitor patients' skin weekly during radiation and guide steroid use, discontinuing it if moist desquamation or other complications arise."

Clinical guideline • Journal • Review • Breast Cancer • Dermatitis • Dermatology • Immunology • Oncology • Solid Tumor

AN UNUSUAL YET A RARE APPENDAGE MANIFESTATION OF SYSTEMIC SCLEROSIS (SSWC 2026) - "She commenced on mycophenolate mofetil, omeprazole and nifedipine and sildenafil unrelenting Raynauds...Cetomacrogol + glycerol was used as soap and moisturizer and had a potent topical corticosteroid (mometasone furoate ointment) for her hands and feet and topical minoxidil to promote growth of her abnormal nails... It is important to be aware of the nail changes in SSc and examination for this should be part of routine examination. Its precise pathophysiology remains to be elu- cidated likewise the appropriate targeted therapy remains an unmet need."

Immunology • Infectious Disease • Ophthalmology • Psoriasis • Scleroderma • Systemic Sclerosis

Case Report: Successful treatment of pityriasis rubra pilaris with deucravacitinib. (PubMed, Front Immunol) - "Initial treatment with topical dinoprostone and mometasone furoate cream was ineffective. This case suggests that deucravacitinib exhibits favorable efficacy and safety in the treatment of PRP. However, due to the low incidence of PRP, which makes large-scale controlled trials difficult, and the lack of recognized treatment guidelines, more clinical studies are needed in the future to further verify the potential of deucravacitinib in the treatment of PRP."

Journal • Dermatology • Infectious Disease • Inflammation • Pruritus • TYK2

Safety and Efficacy of Intralesional 0.5% Triamcinolone Acetonide in 0.2% Fluconazole Solution vs 0.1% Topical Mometasone Furoate With 2% Miconazole Nitrate Cream in the Treatment of Chronic Paronychia: An Intraindividual Randomized Controlled Trial. (clinicaltrials.gov) - P3 | N=21 | Active, not recruiting | Sponsor: Cairo University

New P3 trial

CD21 Things can only get redder! Two cases of allergic contact dermatitis to topical brimonidine tartrate gel. (PubMed, Br J Dermatol) - "Allergic contact blepharitis to brimonidine eye drops is recognized and, more recently, case reports have described patients developing ACD to topical brimonidine gel [Bangsgaard N, Fischer LAN, Zachariae C. Sensitization to and allergic contact dermatitis caused by Mirvaso® (brimonidine tartrate) for treatment of rosacea - 2 cases...He had been using topical Elocon cream daily (mometasone furoate 0.1%) and was diagnosed with steroid-induced rosacea. He was prescribed oral doxycycline, ivermectin cream and brimonidine gel...We would like to raise awareness that in addition to rebound erythema, topical brimonidine gel is also a cause of severe facial ACD. Patch testing to the patient's own medicaments should be performed in suspected cases."

Journal • Allergy • Contact Dermatitis • Dermatitis • Dermatology • Dry Eye Disease • Immunology • Ocular Inflammation • Ophthalmology • Rosacea • CD21

CD09 Complexities of contact dermatitis: lessons from a case of concomitant budesonide and propylene glycol sensitivity. (PubMed, Br J Dermatol) - "Positive reactions on day 4 included propylene glycol 20%, colophony 20%, jasmine absolute Egyptian, tixocortol-21-pivalate 1% in petrolatum, budesonide 0.01% in petrolatum and mometasone furoate ointment...Safe alternatives were recommended, while propylene glycol-containing products such as Dermovate, Metosyn and Synalar were to be avoided...Contact Dermatitis 2019; 81: 280-7). Vigilant allergen avoidance, individualized treatment plans and education are paramount for optimal management to prevent exposure to such allergens in future treatments."

Journal • Allergy • Contact Dermatitis • Dermatitis • Dermatology • Immunology

PA28 Cutaneous sarcoidosis mimicking molluscum contagiosum. (PubMed, Br J Dermatol) - "In July 2023, dupilumab was commenced by the respiratory team for her severe asthma and it had a beneficial effect on her eczema...Lymecycline 408 mg once daily for 2 months and mometasone furoate 0.1% ointment were commenced but the disease continued to progress. We then commenced doxycycline 100 mg daily alongside mometasone furoate 0.1% ointment due to the patient's strong desire to avoid blood tests...Although it is an uncommon presentation, it is important to be aware of it as a differential diagnosis in cases of atypical molluscum contagiosum. This case, in addition to its severity and rarity, has proven challenging to manage given the patient's severe venepuncture phobia."

Journal • Asthma • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Ophthalmology • Pediatrics • Pulmonary Disease • Respiratory Diseases • Sarcoidosis

Impact of Intraocular Lens Design on Refractive Endpoint Selection: A Call for a New Paradigm. (PubMed, Clin Ophthalmol) - "The evidence suggests that a universal refractive target (eg, plano) may be suboptimal for many advanced IOLs and that customized refractive planning-often incorporating mini-monovision or asymmetrical targets-can improve visual outcomes. Future research should aim to standardize defocus measurement techniques and refine classification systems to better guide clinical decision-making."

Journal • Review • Cataract • Ophthalmology

Acupuncture for chronic eczema of blood deficiency stirring wind: a randomized controlled trial (PubMed, Zhongguo Zhen Jiu) - "The control group was treated with mometasone furoate cream, once a day for the first 2 weeks, twice a week for the subsequent 2 weeks...In follow-up, the difference in recurrence rates between the two groups was not statistically significant (P>0.05). Acupuncture can improve the clinical symptoms, TCM syndrome, quality of life of CE patients with blood deficiency stirring wind."

Clinical • Journal • Atopic Dermatitis • Dermatology • Immunology

Adjuvant therapy of severe and/or refractory bullous pemphigoid with immunoadsorption - A prospective monocenter pilot study. (PubMed, J Dtsch Dermatol Ges) - "IA can be considered as a relatively safe and effective adjuvant therapy for patients with severe or refractory BP."

Journal • Bullous Pemphigoid • Dermatology • Dermatopathology • Immunology

Skin Eczema Limited to Transplanted Hand. (PubMed, Clin Cosmet Investig Dermatol) - "Topical mometasone furoate ointment combined with an increased dose of oral prednisone (from 5 mg/day to 10 mg/day) resulted in marked improvement within two weeks, followed by complete resolution after several weeks of regular emollient use. Because eczema can closely mimic rejection, it may complicate post-transplant care and lead to unnecessary changes in immunosuppressive therapy if misdiagnosed. Accurate diagnosis is essential for appropriate management and graft survival."

Journal • Atopic Dermatitis • Contact Dermatitis • Dermatology • Immunology • Transplant Rejection • Transplantation

Efficacy and Safety of Runzaozhiyang Lotion for Chronic Hand Eczema: Protocol for a Randomized Controlled Trial. (PubMed, JMIR Res Protoc) - "Participants in the intervention group will receive RZZYL granules along with a placebo cream of mometasone furoate, whereas the control group will get mometasone furoate cream in combination with a placebo for RZZYL granule...This protocol addresses the limitations of previous research and aims to explore the efficacy and safety of RZZYL in treating CHE through a higher-quality clinical study. It seeks to provide additional treatment options for patients with CHE who are resistant to or have poor responses to current therapies."

Clinical • Clinical protocol • Journal • Atopic Dermatitis • Contact Dermatitis • Dermatology • Immunology • Inflammation • Pruritus

A rare case of infantile gluteal granuloma and tinea incognita in a toddler: diagnostic pitfalls and clinical relevance (EADV 2025) - "The lesion worsened after unsupervised topical use of mometasone furoate and fusidic acid... This case reinforces the importance of early clinical recognition and fungal investigation in persistent inflammatory lesions in infants, especially those previously exposed to topical corticosteroids. It contributes meaningful insight to the limited national literature on IGG and underscores the diagnostic complexity introduced by tinea incognita. The case advocates greater clinical awareness within the fields of pediatric dermatology and clinical mycology."

Clinical • Atopic Dermatitis • Candidiasis • Contact Dermatitis • Dermatitis • Dermatology • Immunology • Infectious Disease • Pediatrics

napkin psoriasis: misdiagnosed as diaper dermatitis, leading to delayed treatment (EADV 2025) - "Based on clinical and histopathological findings, the patient was diagnosed with napkin psoriasis, and was treated with a mixture of petroleum jelly and mometasone furoate cream 0.1% for two weeks, and pure hydrocortisone 0.1% cream was applied to the face, axillary, and genital areas... This case highlights the importance of considering psoriasis in the differential diagnosis of persistent or treatment- resistant diaper rash, especially when lesions extend beyond the diaper area. Early dermatological assessment and appropriate treatment can lead to rapid and effective disease control, even in infancy. This case also highlights the need for high awareness and timely intervention in pediatric dermatology to ensure optimal patient outcomes."

Atopic Dermatitis • Contact Dermatitis • Dermatitis • Dermatology • Immunology • Pediatrics • Psoriasis