KIN004 / Ligand - LARVOL DELTA

Kinnate Biopharma Inc. Adds Two New Drug Candidates to Its Growing Targeted Oncology Pipeline and Provides Cash Runway Guidance (GlobeNewswire) - "Kinnate Biopharma...announced the addition of two new internally developed next generation development candidates to its targeted oncology pipeline....KIN-7136 is designed to be a next generation brain-penetrant MEK inhibitor for investigation in advanced adult solid tumors, primarily non-small cell lung cancer (NSCLC)...Kinnate expects to enter the clinic with KIN-7136 in the second half of 2023, pending U.S. Food and Drug Administration (FDA) clearance on its investigational new drug (IND) application....KIN-8741 is designed to be a highly selective c-MET inhibitor with broad mutational coverage, including acquired resistance mutations, across a variety of solid tumors in which c-MET is overexpressed, such as NSCLC. Kinnate expects to enter the clinic with KIN-8741 in the first half of 2024, pending FDA clearance on its IND application....The company will deprioritize development for its CDK12 program and evaluate strategic alternatives..."

New trial • Pipeline update • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Solid Tumor • Thoracic Cancer