SGC-003
/ Academy of Military Medical Sciences
- LARVOL DELTA
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February 13, 2026
The Novel Soluble Guanylate Cyclase Stimulator Attenuates Acute Lung Injury via Inhibiting Pericyte Phenotypic Transition.
(PubMed, Int J Mol Sci)
- "A novel sGC stimulator, sGC003, was engineered through structural modification of Riociguat. In conclusion, sGC003 mitigates ALI-induced pulmonary inflammation by modulating pericyte differentiation, particularly in preserving microvascular integrity outstanding performance. Its exceptional efficacy suggests that it could potentially serve as a safer and more efficient option as a novel sGC stimulant in the future."
Journal • Acute Lung Injury • Inflammation • Pneumonia • Respiratory Diseases
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