spironolactone/hydrochlorothiazide / Generic mfg. - LARVOL DELTA

Early-Onset Thiazide-Induced Hyponatremia Leading to Seizure in a Middle-Aged Woman Using Aldactazide. (PubMed, Case Rep Nephrol) - "She had started Aldactazide (spironolactone + hydrochlorothiazide 25 mg daily) 3 days earlier, in addition to perindopril/amlodipine and captopril. This case demonstrates that TIH can develop rapidly in middle-aged individuals and may lead to life-threatening neurological complications, including seizures. Clinicians should closely monitor serum sodium during the early phase of thiazide-containing diuretic therapy, particularly when combination regimens such as Aldactazide are prescribed."

Journal • Cardiovascular • CNS Disorders • Critical care • Epilepsy • Heart Failure • Hypertension • Nephrology

"…and the photosensitivity w chlorthalidone is significantly worse. I most commonly use aldactazide (HCTZ/spironolactone)" (@HeartOTXHeartMD)

"Yes - aldactazide , my ❤️❤️❤️! Solves so many of our problems in HTN clinic!" (@thaiscoutinhoCV)