MagneVal (valproate magnesium)
/ BioLink Life Sci
- LARVOL DELTA
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February 25, 2019
The efficacy of magnesium oxide and sodium valproate in prevention of migraine headache: a randomized, controlled, double-blind, crossover study.
(PubMed, Acta Neurol Belg)
- "The mean number of migraine attacks and days per month was 1.72 ± 1.18 and 2.09 ± 1.70, with a mean duration of 15.50 ± 21.80 h in magnesium group and 1.27 ± 1.27 and 2.22 ± 1.96, with a mean duration 13.38 ± 14.10 in valproate group. This study has shown that 500 mg magnesium oxide appears to be effective in migraine prophylaxis similar to valproate sodium without significant adverse effect."
Clinical • Journal • CNS Disorders • Migraine • Pain
October 04, 2013
Pretreatment cognitive deficits and treatment effects on attention in childhood absence epilepsy
(Neurology)
- PMID: 24089388; "More subjects receiving valproic acid (49%) had attention deficits than subjects receiving ethosuximide (32%) or lamotrigine (24%) (p = 0.0006). Parental assessment did not reliably detect attention deficits before or after treatment (p < 0.0001)...This study provides Class I evidence that valproic acid is associated with more significant attentional dysfunction than ethosuximide or lamotrigine in children with newly diagnosed CAE."
Adverse events • Epilepsy
October 05, 2013
The effect of antiepileptic drugs on thyroid function in children
(Seizure)
- PMID: 24091037; P=NA, N=223; "Valproate-treated patients had decreased fT4 and increased TSH levels at months 1, 6, and 12. Carbamazepine-treated patients had decreased fT4 levels at months 1, 6, and 12 and increased TSH levels at months 1, and 6...The frequency of subclinical hypothyroidism at month 12 was 28% in valproate, 21.4% in oxcarbazepine, 18.2% in phenobarbital, 13.9% in carbamazepine, and 0% in levetiracetam groups."
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