Viaskin Milk (DBV135) / DBV Technologies - LARVOL DELTA

Unmasking the Role of Food Elimination Diets in Pediatric Eosinophilic Esophagitis: A Systematic Review (AAAAI-WAO 2025) - "Emerging studies on Viaskin milk (5.6%) showed decreased eosinophil levels without symptom improvement...However, a notable limitation is the scarcity of research on the effectiveness of dietary eliminations in pediatric EoE. In conclusion, this study underscores the importance of exploring and integrating dietary interventions in the treatment of pediatric EoE."

Clinical • Review • Eosinophilic Esophagitis • Food Hypersensitivity • Gastrointestinal Disorder • Immunology • Inflammation • Pediatrics

Varying Doses of Epicutaneous Immunotherapy With Viaskin Milk Versus Placebo in Children With Cow's Milk Allergy: A Randomized Clinical Trial. (PubMed, Pediatrics) - No abstract available

Clinical • Journal • Allergy • Food Hypersensitivity • Immunology

Varying Doses of Epicutaneous Immunotherapy With Viaskin Milk vs Placebo in Children With Cow's Milk Allergy: A Randomized Clinical Trial. (PubMed, JAMA Pediatr) - P1/2 | "Further research is needed to explore Viaskin milk as a viable treatment option for children with IgE-mediated CMA. ClinicalTrials.gov Identifier: NCT02223182."

Clinical • Journal • Allergy • Food Hypersensitivity • Immunology

Efficacy and Safety of Viaskin Milk in Children With IgE-Mediated Cow's Milk Allergy (clinicaltrials.gov) - P1/2; N=198; Completed; Sponsor: DBV Technologies; Active, not recruiting ➔ Completed

Clinical • Trial completion • Allergy • Food Hypersensitivity • Immunology

"And also, very soon, @DBVTechnologies will create a patch to solve the problem of dairy allergie (Viaskin Milk). As Viaskin Peanut and Viaskin Egg. 😉👍💪" (@RassalleAxel)

Identification of potential CD4+ T-cell pathways associated with epicutaneous milk desensitization of eosinophilic esophagitis patients (AAAAI 2020) - "However, following the open-label extension of the Study Efficacy and Safety of the Viaskin® Milk in milk-induced Eosinophilic Esophagitis (SMILEE), 47% of patients tolerated milk without recrudescence of esophageal eosinophilia... Active mucosal disease in EoE is associated with a Th2-predominant expression pattern in peripheral CD4+ T cells, and this shifts toward a Th1-predominant expression pattern following EPIT. This data additionally suggests common pathways shared between EPIT and other forms of immunotherapy, and may help to identify an EoE population that will benefit from EPIT."

Clinical • IO Biomarker