Reatix Kit (atazanavir/ritonavir and tenofovir/emtricitabine) / Emcure - LARVOL DELTA

Switching Tenofovir HIV Regimens Can Cause Weight Gain (MedPageToday) - "I do want to stress that this study was supported by Gilead Sciences, and it was on a very concerning question that we're having these days for us in the HIV community: what is happening with weight change in people who switched from tenofovir disoproxil fumarate to tenofovir alafenamide? And essentially this is now over the last two years, we've been seeing a study from the longitudinal OPERA cohort, we have seen studies in the advanced study. We have seen this in multiple other settings that TAF is associated with weight gain, especially when it is in tandem with integrase inhibitors."

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Testing the Boundaries of 2-Drug ART: Early Data on Efficacy and Safety for Rapid ART (Clinical Care Options) - "During the past few years, there has been an increasing interest in initiating ART at the time of first HIV care visit-the so-called rapid start or same day start strategy. Randomized, controlled studies in resource-limited settings have shown that rapid start results in shorter time to virologic suppression, enhanced engagement in care, and higher rates of virologic suppression. In resource-rich communities, observational studies show that rapid start ART is feasible and results in good virologic suppression. Although there are no definitive data from randomized controlled trials in more resourced settings showing that rapid start results in improved linkage and retention to care, there is considerable experience demonstrating that the risks of this strategy are very low."

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