OPB-171775
/ Otsuka
- LARVOL DELTA
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June 12, 2024
A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors.
(PubMed, Clin Cancer Res)
- "These findings suggest that OPB-171775, with its significant efficacy, could potentially serve as a novel and effective treatment option for advanced GISTs, particularly those resistant to TKIs."
Journal • Stroma • Gastrointestinal Cancer • Gastrointestinal Disorder • Gastrointestinal Stromal Tumor • Oncology • Sarcoma • Targeted Protein Degradation • KIT • PDE3A • PDGFRA • SLFN
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