CTS3157
/ CytosinLab
- LARVOL DELTA
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March 14, 2023
CTS3157, a novel MTA-cooperative PRMT5 inhibitor for targeting MTAP-deleted human tumors
(AACR 2023)
- "In summary, MTAPnull-selective PRMT5 inhibitor CTS3157 showed strong and durable antitumor responses in vitro and in vivo in MTAP-deleted tumors across diverse lineages. CTS3157 is an effective and promising therapeutics against MTAP-deleted tumors."
Oncology • CDKN2A • CDKN2B • MTAP • PRMT5
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