orBec (beclomethasone dipropionate oral) / Soligenix - LARVOL DELTA

[VIRTUAL] IMPACT OF UPPER AND LOWER ACUTE GASTROINTESTINAL GRAFT-VERSUS-HOST DISEASE ON GRADING AND OUTCOME OF ALLOGENEIC STEM CELL TRANSPLANTATION: A RETROSPECTIVE ANALYSIS IN 122 CONSECUTIVE PATIENTS (EBMT 2020) - "No patients developed lower GI aGVHD after diagnosis of upper GI aGVHD: all patients with isolated upper GI aGVHD obtained a complete response with oral beclomethasone... GI aGVHD remains an important obstacle to the success of allo-HSCT, in particularly lower GI aGVHD represents a potentially fatal complication of allo-HSCT. Upper GI aGVHD presents a minor impact on survival and patients with aGVHD classified as grade 2A have similar outcome as those with lower grade aGVHD."

Retrospective data • Gastrointestinal Disorder • Graft versus Host Disease • Immunology • Transplantation

[VIRTUAL] IMPACT OF UPPER AND LOWER ACUTE GASTROINTESTINAL GRAFT-VERSUS-HOST DISEASE ON GRADING AND OUTCOME OF ALLOGENEIC STEM CELL TRANSPLANTATION: A RETROSPECTIVE ANALYSIS IN 122 CONSECUTIVE PATIENTS (EBMT 2020) - "No patients developed lower GI aGVHD after diagnosis of upper GI aGVHD: all patients with isolated upper GI aGVHD obtained a complete response with oral beclomethasone... GI aGVHD remains an important obstacle to the success of allo-HSCT, in particularly lower GI aGVHD represents a potentially fatal complication of allo-HSCT. Upper GI aGVHD presents a minor impact on survival and patients with aGVHD classified as grade 2A have similar outcome as those with lower grade aGVHD."

Retrospective data • Gastrointestinal Disorder • Graft versus Host Disease • Immunology • Transplantation

[VIRTUAL] IMPACT OF UPPER AND LOWER ACUTE GASTROINTESTINAL GRAFT-VERSUS-HOST DISEASE ON GRADING AND OUTCOME OF ALLOGENEIC STEM CELL TRANSPLANTATION: A RETROSPECTIVE ANALYSIS IN 122 CONSECUTIVE PATIENTS (EBMT 2020) - "No patients developed lower GI aGVHD after diagnosis of upper GI aGVHD: all patients with isolated upper GI aGVHD obtained a complete response with oral beclomethasone... GI aGVHD remains an important obstacle to the success of allo-HSCT, in particularly lower GI aGVHD represents a potentially fatal complication of allo-HSCT. Upper GI aGVHD presents a minor impact on survival and patients with aGVHD classified as grade 2A have similar outcome as those with lower grade aGVHD."

Retrospective data • Gastrointestinal Disorder • Graft versus Host Disease • Immunology • Transplantation

[VIRTUAL] IMPACT OF UPPER AND LOWER ACUTE GASTROINTESTINAL GRAFT-VERSUS-HOST DISEASE ON GRADING AND OUTCOME OF ALLOGENEIC STEM CELL TRANSPLANTATION: A RETROSPECTIVE ANALYSIS IN 122 CONSECUTIVE PATIENTS (EBMT 2020) - "No patients developed lower GI aGVHD after diagnosis of upper GI aGVHD: all patients with isolated upper GI aGVHD obtained a complete response with oral beclomethasone... GI aGVHD remains an important obstacle to the success of allo-HSCT, in particularly lower GI aGVHD represents a potentially fatal complication of allo-HSCT. Upper GI aGVHD presents a minor impact on survival and patients with aGVHD classified as grade 2A have similar outcome as those with lower grade aGVHD."

Retrospective data • Gastrointestinal Disorder • Graft versus Host Disease • Transplantation

Efonidipine-Induced Exanthematic Drug Eruption and Literature Review. (PubMed, J Cardiovasc Pharmacol) - "In view of her hypertension and left anterior descending artery stenosis, she was initiated on aspirin, clopidogrel, atorvastatin, pantoprazole, nebivolol, aldactone, and efonidipine a week ago. Her presenting complaints were initially managed with parenteral pheniramine maleate and hydrocortisone...She was prescribed topical beclomethasone and oral antihistamines for better control of her symptoms...World Health Organization-Uppsala Monitoring Centre causality assessment criteria indicated a "certain" association. To the best of the knowledge of the authors, this is one among the first reported cases of efonidipine-induced exanthematic drug eruption."

Journal • Dermatology • Dermatopathology

Pyostomatitis vegetans in a pediatric patient with ulcerative colitis: case report of a rare pediatric inflammatory bowel disease extraintestinal manifestation and review of the literature. (PubMed, Eur J Gastroenterol Hepatol) - "Bloody diarrhea was treated with oral beclomethasone, with rapid remission of ulcerative colitis and disappearance of pyostomatitis vegetans. After 2 years, ulcerative colitis is in sustained remission with oral mesalamine and pyostomatitis vegetans has not recurred. Pyostomatitis vegetans is considered a marker of ulcerative colitis relapse among adult population, and although very few pediatric cases are described, it is very important to remember it in the differential diagnosis of the oral manifestations and comorbidities of inflammatory bowel diseases."

Clinical • Journal