hydrocodone IR (PF6129) / Ensysce Biosciences - LARVOL DELTA

In silico drug repurposing against SARS-CoV-2 using an integrative transcriptomic profiling approach: Hydrocortisone and Benzhydrocodone as potential drug candidates against COVID-19. (PubMed, Infect Genet Evol) - "Finally, molecular docking of up-regulated proteins and all FDA-approved drugs revealed that both Hydrocortisone and Benzhydrocodone possess high binding affinity for all pro-viral proteins. The suggested repurposed drugs should be subject to complementary in vitro and in vivo experiments in order to be evaluated in detail prior to clinical studies in potential management of COVID-19."

Journal • Infectious Disease • Novel Coronavirus Disease • Respiratory Diseases • ADAR • HBEGF • ICAM1 • IFI35 • IRF2 • MMP9 • STAT3 • USP18