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February 03, 2018
PTSD-Related Behavioral Traits in a Rat Model of Blast-Induced mTBI Are Reversed by the mGluR2/3 Receptor Antagonist BCI-838.
(PubMed, eNeuro)
- "Treatment with BCI-838 also increased neurogenesis in the dentate gyrus (DG) of blast-exposed rats. The safety profile of BCI-838 together with the therapeutic activities reported here, make BCI-838 a promising drug for the treatment of former battlefield Warfighters suffering from PTSD-related symptoms following blast-induced mTBI."
Journal • Preclinical • Biosimilar • CNS Disorders • Depression • Mood Disorders • Post-traumatic Stress Disorder
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