albendazole / Generic mfg. - LARVOL DELTA

Albendazole loaded chitosan nanoparticle conjugated with hyaluronic acid for the treatment of psoriasis. (PubMed, Drug Dev Ind Pharm) - "In-vivo studies conducted on Balb/c mice showed reduced Psoriasis Area Severity Index, Spleen weight as well as reduced keratinocyte proliferation in histopathological studies. In conclusion, developed novel formulation of Albendazole reduced keratinocyte proliferation making it a possible effective strategy in the management of psoriasis."

Journal • Dermatology • Immunology • Oncology • Psoriasis • CD44

Discovery of novel repurposed anthelminthics against Trichinella spiralis and albendazole-resistant nematodes through metabolomics-guided virtual screening. (PubMed, Curr Res Parasitol Vector Borne Dis) - "Lumacaftor, entrectinib, and fluspirilene showed the lowest binding energies and were tested in vitro. Importantly, entrectinib also killed both ABZ-sensitive and ABZ-resistant Caenorhabditis elegans at lower concentrations than ABZ, demonstrating potent activity against resistant nematodes. Our findings suggest that entrectinib is a promising candidate for a novel anthelmintic, with potential to overcome ABZ resistance in trichinellosis and other parasitic infections."

Journal • Infectious Disease • Metabolic Disorders • Musculoskeletal Pain • Pain

Unveiling of phytochemicals, antioxidants, cytotoxic effects and anthelmintic potency of green tea (Camellia sinensis) beverage against albendazole resistant Hamonchus contortus. (PubMed, Sci Rep) - No abstract available

Journal

Palliative Management of Advanced Breast Carcinoma Complicated by Myiasis: First Case Report From Bangladesh. (PubMed, Clin Med Insights Case Rep) - "She was treated with morphine, flucloxacillin, ivermectin, and albendazole, which resulted in significant symptomatic relief...This report underscores the importance of early recognition and integrated management of malignant wound myiasis, particularly in resource-constrained environments. It also draws attention to the broader psychosocial impacts of such conditions and the essential role of end-of-life care in mitigating suffering."

Journal • Breast Cancer • HER2 Breast Cancer • HER2 Positive Breast Cancer • Infectious Disease • Oncology • Pain • Palliative care • Solid Tumor • HER-2

Medical, Surgical, and Combined Approaches in Pediatric Hydatid Liver Disease: A Systematic Review. (PubMed, Pediatr Rep) - "Treatment efficacy correlated significantly with cyst size: small cysts (6 cm) required surgical management...The findings recommend standardized protocols incorporating cyst size, location, and complexity as key decision points, with expanded access to minimally invasive techniques. Future research should focus on prospective comparative studies with standardized outcome measures."

Journal • Review • Hepatology • Pain • Pediatrics

Duplex Real-Time qPCR Assay Targeting β-Tubulin SNPs for Detection of Albendazole Resistance in Haemonchus contortus. (PubMed, Vet J) - "Sequencing of seven randomly selected samples produced results identical to the qPCR findings, further confirming the assay's sensitivity and accuracy. This study successfully established a rapid, sensitive, and specific duplex qPCR assay capable of accurately discriminating albendazole-resistant genotypes of H. contortus, providing an effective tool for anthelmintic selection and resistance surveillance in veterinary clinical practice."

Journal • Infectious Disease

High prevalence of soilborne and waterborne parasitic infections among schoolchildren, Belén District, Loreto Region, Peru. (PubMed, Parasites Hosts Dis) - "Mass deworming was initiated with albendazole 400 mg, 3 times a year, in conjunction with health education and environmental sanitation...A notable finding in this study was that soilborne and waterborne parasites are both highly prevalent among schoolchildren in the floating villages of the Belén District, Loreto Region. Sustained mass deworming is urgently needed and the WASH program is crucial."

Journal • Hematological Disorders • Infectious Disease

Benzimidazole inhibits Haemonchus contortus microtubule dynamics by intradimer structural changes observed by in silico modeling. (PubMed, J Biomol Struct Dyn) - "These hydrogen bonds could reduce the negative partial charge of E198, which is critical for interacting with albendazole. We postulate that charge modulation or an amino acid change of E198 prevent its interaction with albendazole, leading to resistance."

Journal

Calcified frontal neurocysticercosis presenting with acute psychosis in a non-endemic context: a case report. (PubMed, Front Psychiatry) - "He was co-managed by neurology and psychiatry teams and initiated on albendazole, dexamethasone, lamotrigine, risperidone, and lorazepam. Clinical improvement following combined antiparasitic, anti-inflammatory, antiepileptic, and antipsychotic therapy supports the value of early multidisciplinary management, while recognizing that symptom resolution likely reflects multifactorial influences. As global migration increases, clinicians in non-endemic regions should remain aware of NCC as a potential contributor to secondary psychosis."

Journal • CNS Disorders • Epilepsy • Infectious Disease • Mental Retardation • Psychiatry

When Appearances Deceive: A Case Report of Neurocysticercosis Masquerading As Tuberculoma. (PubMed, Cureus) - "Treatment with albendazole and corticosteroids resulted in complete seizure control without recurrence. This case underscores the necessity for meticulous clinic-radiological correlation and increased diagnostic vigilance to prevent misdiagnosis and unnecessary treatment, particularly in resource-constrained environments."

Journal • CNS Disorders • Epilepsy • Infectious Disease • Pulmonary Disease • Respiratory Diseases • Tuberculosis

DFT and molecular docking-guided investigation of mixed-ligand octahedral Fe(III) and Cu(II) Schiff-base and albendazole complexes with antimicrobial potential. (PubMed, J Comput Aided Mol Des) - "This was consistent with its observed in vitro antimicrobial properties. In general, these mixed transition metal complexes, particularly CuHLAB, show strong antimicrobial activity, which provides an important approach to conserving water, soil, and public health as well as potentially thwarting economic loss."

Journal

Insights from a fatal case of disseminated albendazole refractory Annacaliia algerae myositis (ESCMID Global 2026) - No abstract available

Clinical • Immunology • Myositis

Albendazole pharmacokinetics in plasma and cystic tissue of human cystic and alveolar echinococcosis (ESCMID Global 2026) - No abstract available

PK/PD data

Cytopenia Following Albendazole Use: A Real-World Observation (APASL 2026) - No abstract available

Clinical • Real-world • Real-world evidence • Hematological Disorders

Laparoscopic spleen-preserving management of a large primary splenic hydatid cyst: a case report. (PubMed, Int J Surg Case Rep) - "After 5 days of preoperative albendazole according to institutional protocol, laparoscopic cyst evacuation, partial pericystectomy, and omentoplasty were performed using a three-port technique...Meticulous use of scolicidal agents and controlled aspiration prevented spillage and recurrence. This case highlights that laparoscopic spleen-preserving surgery is feasible and safe for large primary splenic hydatid cysts in experienced hands, even in technically challenging scenarios."

Journal • Infectious Disease • Pain • CRP

MULTIMODAL IMAGING GUIDED SURGICAL RESOLUTION OF CARDIAC HYDATID CYST IN THE LEFT VENTRICLE (ACC 2026) - "Multimodality imaging established the diagnosis and guided safe resection despite negative serology. Early surgery plus albendazole therapy achieved full clinical recovery."

Cardiovascular • Heart Failure

ISOLATED CARDIAC HYDATID CYST WITH SEVERE TRICUSPID REGURGITATION SURGICAL MANAGEMENT OF TWO PATHOLOGIES IN A SINGLE PROCEDURE (ACC 2026) - "Recovery was uneventful, and albendazole therapy was continued Decision-Making: The hydatid cyst carried a high risk of catastrophic complications, and the coexisting severe tricuspid regurgitation added to the clinical burden... Isolated cardiac hydatid cysts may coexist with valvular disease, complicating symptom attribution. In such cases, combined surgical excision and valve repair is justified, as it eliminates the risk of hydatid-related complications and restores valve function, leading to excellent clinical outcomes."

Cardiovascular • Pulmonary Disease

ZOONOTIC MYOCARDITIS SECONDARY TO TRICHINELLA SPIRALIS INFECTION (ACC 2026) - "Therapy was initiated with albendazole, with rapid symptom improvement and reductions in total creatine kinase and troponin levels... Trichinella spiralis can rarely present with myocarditis. In the event of atypical chest pain and elevated troponins in a patient with the classical clinical symptoms, the patient should be immediately treated and evaluated with CMR."

Cardiovascular • Eosinophilia • Infectious Disease • Inflammation • Musculoskeletal Pain

Evaluation of albendazole-induced genotoxicity using the somatic mutation and recombination test (SMART): implications for chemotherapy of neglected tropical parasitic diseases. (PubMed, Acta Trop) - "These findings suggest that neither albendazole nor its metabolites generated in the HB cross induced detectable loss of heterozygosity events in imaginal disc cells. Overall, the findings demonstrate that ABZ does not induce genotoxic effects in the wing SMART assay, although further studies using complementary endpoints are warranted."

Journal

Green Synthesized Zinc Oxide Nanoparticles as a Promising Adjuvant to Albendazole in the Management of Hydatid Cyst Disease: Molecular and Biochemical Insights. (PubMed, Acta Parasitol) - No abstract available

Journal

Anthelmintic resistance on meat goat properties in Queensland and New South Wales, Australia, with a comparison of statistical methods. (PubMed, Vet Parasitol Reg Stud Reports) - "This study identified the first field cases of resistance, classifications to several anthelmintics: Moxidectin (MOX) on 70% of properties, Monepantel (MPL) + Abamectin (ABA) on 50%, Derquantel (DER) + ABA on 33%, ABA+Oxfendazole (OXF) + Levamisole (LEV) on 50% and ABA+Closantel (CLOS) + LEV+Albendazole (ABZ) on 50%. This has significant implications for the longevity of these treatments and poses a serious risk to successful control of GIN in goats using chemicals. The continued reliance on anthelmintics is not sustainable, the incorporation of non-chemical control management practices should be encouraged for all goat producers."

Clinical • Journal • Infectious Disease

Cost-Effectiveness of Triple Versus Dual-Drug Therapy for Elimination of Lymphatic Filariasis in India. (PubMed, Value Health Reg Issues) - "We found that IDA is cost-effective, when compared with DA, offering better health outcomes and long-term cost savings. These findings support the adoption of IDA in Mass Drug Administration programs, promoting efficient resource use and advancing LF elimination goals by 2027."

HEOR • Journal

A rare intramuscular hydatid cyst of the gluteus: a case report. (PubMed, Int J Surg Case Rep) - "The patient underwent en bloc pericystectomy followed by albendazole treatment for 3 months, after which the patient was asymptomatic and disease-free as evident on repeat MRI...Primary muscle hydatidosis is rare but responds well to a combination of surgery and anthelmintic medications. Complete and intact cyst removal is necessary to avoid complications and recurrence."

Journal • Cardiovascular • Infectious Disease • Inflammation • Oncology • Orthopedics • Pain

Acute Cauda Equina Syndrome Due to Primary Lumbar Spinal Hydatid Cyst: A Rare Case. (PubMed, J Orthop Case Rep) - "The patient underwent posterior decompression, fixation, and complete cyst excision followed by albendazole therapy, with significant neurological improvement on follow-up. Primary lumbar spinal hydatid disease, though rare, should be considered in endemic regions when evaluating cystic spinal lesions. Early surgical decompression combined with antihelminthic therapy is essential to prevent permanent neurological deficits."

Journal • Gastrointestinal Disorder • Infectious Disease • Inflammatory Bowel Disease

Albendazole pharmacokinetics in plasma, intra-cystic fluid and cystic tissue of human cystic and alveolar echinococcosis (clinicaltrialsregister.eu) - P1 | N=24 | Completed | Sponsor: Medical University Of Vienna | Recruiting ➔ Completed

Trial completion