rExenatide-4 / CSPC Pharma - LARVOL DELTA

The pancreatic cancer secreted REG4 promotes macrophage polarization to M2 through EGFR/AKT/CREB pathway. (PubMed) - Oncol Rep - "The conditioned medium of macrophages treated with rREG4 promoted the proliferation and invasion of pancreatic cancer cell lines. REG4, overexpressed in PDAC and secreted by cancer cells, promoted macrophage polarization to M2, through at least in part, activation of ERK1/2 and CREB and changed the microenvironment to facilitate cancer growth and metastasis."

Journal • Biosimilar • Oncology • Pancreatic Cancer

Clinicopathological features of myeloid sarcoma and DLBCL in the breast: a comparative study (PubMed, Zhonghua Bing Li Xue Za Zhi) - "Tumor resection, chemotherapy, radiotherapy and donor lymphocyte infusion are recommended for treatment. The prognosis is poor."

Clinical • Journal • Retrospective data

"Thx @DrLisaIsaac @JenniferTyrre14 for your video & inaugural #PedsTransitionalPainService to reduce pain in kids and promote safe #opioid use. @SickKidsNews @DrCChambers @adfurlan @picardonhealth @ChadLarabie @Drhaclarke @PedsAnesthesia @PedsPainMed @PediAnesthesia @CanadianPain" (@DrFCampbell)

Video