hydrocortisone/pramoxine / Generic mfg. - LARVOL DELTA

Innovative Hydrocortisone Acetate and Pramoxine Hydrochloride Topical Cream Formulations for Anorectal Conditions: Enhanced In Vitro Release Profile. (PubMed, Pharmaceutics) - "This medication combination (hydrocortisone and pramoxine) is the first generic drug product utilized to alleviate minor pain, itching, swelling, and discomfort associated with anorectal conditions such as hemorrhoids. Quantitative content of the release tests of the active ingredients in the cream, assay tests, antimicrobial preservative efficacy, and stability tests were carried out by high-sensitivity liquid chromatography. In conclusion, the cream formulations developed in this study have the potential to offer more effective treatment compared to reference products in terms of both in vitro release rates, and their reliability and validity were confirmed through validation studies."

Journal • Preclinical • Gastroenterology • Gastrointestinal Disorder • Pain

The effects of cryotherapy on perineal pain after childbirth: A systematic review and meta-analysis. (PubMed, Midwifery) - "Cryotherapy can be an effective non-pharmacological nursing intervention to reduce pain after childbirth."

Journal • Retrospective data • Review • Pain