Quadracel (Diphtheria, tetanus, pertussis & polio vaccine) / Sanofi - LARVOL DELTA

Quantitative microcapillary electrophoresis immunoassay (mCE IA) for end-to-end analysis of pertactin within in-process samples and Quadracel® vaccine. (PubMed, J Pharm Biomed Anal) - "This allows for seamless end-to-end analysis of PRN from fermenter harvest, through to complex downstream process samples to adjuvanted drug products. Finally, for the first time the developed and qualified mCE IA method was shown to quantify PRN throughout the entire manufacturing process to provide rapid feedback for process optimizations allowing for accurate yield and step-loss calculations."

Journal • Infectious Disease • Pertussis • Respiratory Diseases