AR100 / ARJIL Pharma - LARVOL DELTA

Genomic Alterations in Quadruple-Negative Breast Cancer Tumors. (PubMed, Int J Mol Sci) - "A total of 54 TNBC cases were categorized as TNBC with 100% AR expression (TNBC AR-100%) or QNBC, TNBC with 0% AR expression (TNBC AR-0%)...These results suggest that, at both molecular and genomic levels, the two groups are distinct, holding QNBC tumors more aggressive characteristics, genomic instability, and particular impairments in HRR and cancer-related pathways. In terms of actionability, these differences could potentially be leveraged through different combinations of therapies."

Journal • Breast Cancer • Oncology • Solid Tumor • Triple Negative Breast Cancer • AR • HRD

Deep learning-based pressure injury staging: a multicentre study involving 59 hospitals. (PubMed, J Glob Health) - "Among the models evaluated, Mask R-CNN with Swin Transformer demonstrated the highest overall performance (mAP = 0.894, AP50 = 0.900, AP = 0.757, AR100 = 0.792), surpassing the corresponding metrics of the other two models...The proposed deep learning-based system showed promising performance in pressure injury staging and may provide meaningful support for clinical decision-making. Future studies should focus on further validation and refinement using larger and more diverse data sets to enhance their applicability in routine clinical practice."

Journal • Retrospective data

Hierarchical Semantic Transmission and Lyapunov-Optimized Online Scheduling for the Internet of Vehicles. (PubMed, Sensors (Basel)) - "To address cross-scheme fairness, we report resource utilization under a fixed kbps/fps physical budget and evaluate robustness using a combination of a lightweight task-proxy metric and COCO-style Average Recall (AR100) under ROI-only evaluation...The Lyapunov-based online scheduler enables intelligent, signal-to-noise ratio (SNR)-adaptive switching between coarse and fine semantic levels, ensuring robust perception under varying channel quality. Under strict physical-budget constraints and unreliable channel conditions, joint source-channel coding (JSCC) exhibits significantly stronger task robustness than conventional schemes: at 0 dB SNR, the task-proxy detection rate improves by nearly 47 percentage points over the uncoded baseline."

Journal

Usability Test for a Smart Glass-Based Application to Support Nurses' Hospital Admission Tasks. (PubMed, Comput Inform Nurs) - "The smart glasses used in this study were AR100 and DE100 from Dynabook...However, we found usability issues related to the input method and distraction risks owing to the presence of the display, and the required application functionalities may vary depending on the nurses' capabilities. Although smart glasses can potentially improve the efficiency of nurses' hospital duties, further enhancements in usability are necessary."

Journal

A Study for AR100DP1 in Mild to Moderate Atopic Dermatitis (AD) (clinicaltrials.gov) - P1/2 | N=17 | Terminated | Sponsor: Arjil Pharmaceuticals LLC | N=35 ➔ 17 | Not yet recruiting ➔ Terminated; Due to the two AEs in Phase IIa study, recruiting was stopped for safety sake. The study was currently terminated.

Enrollment change • Trial termination • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Spatial resolution, noise properties and detectability index of a deep learning reconstruction algorithm for dual-energy CT of the abdomen. (PubMed, Med Phys) - "DE imaging with DLR maintained spatial resolution and reduced noise magnitude while displaying less change in noise texture than IR. The detectability index was also higher with DLR than iterative reconstruction, suggesting superiority in detectability of iodinated contrast. Despite these trends being consistent with those previously established for SE imaging, there were some noteworthy differences. For DE imaging there was no improvement in resolution compared to iterative reconstruction and a change in noise texture. DE imaging with low keV and DLR had superior detectability to SE DLR at the high dose but was not better than SE-80 kV at low dose."

Journal

Effects of gas saturation and sparging on sonochemical oxidation activity in open and closed systems, part II: NO/NO generation and a brief critical review. (PubMed, Ultrason Sonochem) - "The absorption of N from the air resulted in high generation of NO and NO for Ar 100 % and Ar/O mixtures under the saturation/open mode...From a summary of the results and findings of previous studies, it was revealed that the observations of NO + NO could be more appropriate for investigating the NO and NO generation characteristics. In addition, HO/NO/NO related activity rather than HO activity was suggested to quantify the OH radical activity more appropriately in the presence of N."

Journal • Review

Species identification by MALDI-TOF MS and gap PCR-RFLP of non-aureus Staphylococcus, Mammaliicoccus, and Streptococcus spp. associated with sheep and goat mastitis. (PubMed, Vet Res) - "gallolyticus (1.8%) according to both methods (AR 100%)...haemolyticus, minor NAS species including Staph. microti, and species of the novel genus Mammaliicoccus."

Journal • Infectious Disease