FS102 / Ligand, Sino Biopharm - LARVOL DELTA

Aspergillus sydowii: Genome Analysis and Characterization of Two Heterologous Expressed, Non-redundant Xylanases. (PubMed, Front Microbiol) - "One of the best xylanase producing strains proved to be an Aspergillus sydowii strain from shrimp shell (Fsh102), showing a specific activity of 0.6 U/mg...With site directed mutagenesis, the active site residues in both enzymes were confirmed. The presented activity and stability justify the classification of both xylanases as highly interesting for further development."

Journal

Phase 1, Multiple Ascending Dose Study of Anti-HER2 FCAB FS102 in HER2 Positive Solid Tumors (Anti HER2 Fcab) (clinicaltrials.gov) - P1; N=30; Completed; Sponsor: Bristol-Myers Squibb; N=21 ➔ 30

Enrollment change • Biosimilar • Breast Cancer • Gastric Cancer • Gastrointestinal Cancer • HER2 Breast Cancer • Oncology • Solid Tumor

"Marie Curie was the first woman to win the noble prize! Such an inspiration! #FS102" (@AlexandraGlava3)

Clinical