LCB02A
/ LigaChem Biosci
- LARVOL DELTA
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March 06, 2024
LCB02A an antibody drug conjugate (ADC) targeting CLDN18.2 expressing solid tumors
(AACR 2024)
- "Preliminary toxicity assessment in cynomolgus monkeys (CLDN18.2 cross-reactive species) demonstrated that LCB02A was well tolerated, with repeat doses of up to 60 mg/kg. In conclusion, LCB02A is a promising ADC for the treatment of CLDN18.2 expressing solid tumors including gastric cancer (GC) and pancreatic ductal adenocarcinoma (PDAC)."
Gastric Cancer • Gastrointestinal Cancer • Oncology • Pancreatic Cancer • Pancreatic Ductal Adenocarcinoma • Solid Tumor • CLDN18
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