Decoderm (fluprednidene acetate) / Almirall - LARVOL DELTA

Sex differences of fall-risk-increasing drugs in the middle-aged and elderly: a descriptive, cross-sectional study of FDA adverse event reporting system. (PubMed, Sci Rep) - "For males, the top 3 signals with the highest ROR were fluprednidene acetate, potassium hydroxide, ketazolam (ROR: 216.86, 108.43, 108.43), while the top 3 signals with the highest IC025 were clomethiazole, piribedil, melperone (IC025: 3.31, 3.24, 2.99). We offered a series of FRIDs and suggested their sex differences in falls through the FAERS. In the future, it is essential to balance the inclusion of women and men, and analyse sex-stratified for FRIDs."

Adverse events • Journal • Observational data • Retrospective data • Cardiovascular • Musculoskeletal Diseases

Graphormer supervised de novo protein design method and function validation. (PubMed, Brief Bioinform) - "Thus, the GPD method could be used for the de novo design of industrial enzymes and protein drugs. The code was released at https://github.com/decodermu/GPD."

Journal