dorzolamide/latanoprost (ALZ-1101) / Alleanza - LARVOL DELTA

Assessment of the readability and quality of online patient education materials for the medical treatment of open-angle glaucoma. (PubMed, BMJ Open Ophthalmol) - "The top 10 relevant Google searches for nine glaucoma medications (timolol, brimonidine, apraclonidine, dorzolamide, latanoprost, bimatoprost, travoprost, tafluprost and brinzolamide) and three generic searches were analysed for readability and accountability. Pearson's correlation coefficient showed a correlation between the FRES and accountability score (r=0.19, p=0.045). The majority of online patient education materials for the medical treatment of glaucoma are written at a level too difficult for the general population and fail to meet accountability standards."

Journal • Glaucoma • Ophthalmology

Efficacy, Safety and Patient-Reported Outcomes with Preservative-Free (PF) Tafluprost or PF-Dorzolamide/Timolol Compared with Preserved Latanoprost: A Prospective Multicenter Study in Korean Glaucoma Patients with Ocular Surface Disease. (PubMed, Pharmaceuticals (Basel)) - "No new safety concerns were observed. PF-tafluprost and PF-dorzolamide/timolol showed statistically and clinically significant reductions in OSDI compared with P-latanoprost in Korean glaucoma patients with OSD."

Clinical • Journal • Patient reported outcomes • Dry Eye Disease • Glaucoma • Ophthalmology

OCT ANGIOGRAPHY, VISUAL FIELD AND RNFL WITH VARIOUS MEDICATIONS IN HYPERTENSIVE GLAUCOMAS. (PubMed, Cesk Slov Oftalmol) - "The sample, consisting of 36 HTG patients (72 eyes), was divided into three subgroups: In the first group, patients were treated with combination therapy (latanoprost + timolol, latanoprost + dorzolamide + timolol, dorzolamide + timolol)...In the second group, patients were treated with beta-blockers (carteolol, betaxolol, timolol)...In the third group, patients were treated with prostaglandins (latanoprost, bimatoprost)...The measured values of the third group were taken as baseline. In the statistical analysis, we have found differences in visual field in the combination treatment group (p = 0.0006) and differences were recorded for RNFL in the beta-blocker group (p = 0.04)."

Journal • CNS Disorders • Glaucoma • Ophthalmology

[VIRTUAL] Eye Pain During Hemodialysis: Ocular Dialysis Disequilibrium? (KIDNEY WEEK 2021) - "He was on atropine sulfate, prednisolone acetate, latanoprost, dorzolamide/timolol, and brimonidine tartrate eye drops...While acetazolamide is an effective treatment for raised IOP, it’s efficacy and safety in ESRD remains unknown...Our patient had resolution of ocular dialysis disequilibrium with decrease in blood and dialysate flow rates, increase in dialysate sodium, and decrease in dialysate temperature. Increase in ultrafiltration may also reduce risk of ocular dialysis disequilibrium by raising extracellular oncotic pressure."

Chronic Kidney Disease • Diabetes • Diabetic Nephropathy • Glaucoma • Metabolic Disorders • Nephrology • Ophthalmology • Pain • Renal Disease

Microinvasive medical therapies needed for glaucoma patients (Healio) - "We have several approved microinvasive glaucoma surgeries approved....Critical to the future best interests of our patients is to develop a way to diagnose the undiagnosed glaucoma patient and then treat all victims of this potentially blinding disease in a cost-effective fashion that does not require the patients’ compliant participation. Neither of these is an easy goal to achieve, but incremental progress is being made toward both of these challenges."

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