triamcinolone acetonide topical / Generic mfg. - LARVOL DELTA

A Case Report of Acute Generalized Pustular Bacterid Preceded by Tinea Pedis. (PubMed, Case Rep Dermatol) - "After 1 week of combination therapy with intravenous cefuroxime sodium and topical triamcinolone acetonide and econazole nitrate cream, the skin lesions showed significant improvement. This case highlights that for patients presenting with acute generalized pustular eruptions accompanied by tinea pedis, AGPB should be included in the differential diagnosis. Early recognition and targeted treatment can lead to a favorable prognosis."

Journal • Dermatology • Infectious Disease • Vasculitis

Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus (clinicaltrials.gov) - P4 | N=60 | Recruiting | Sponsor: All India Institute of Medical Sciences, Bhubaneswar | Not yet recruiting ➔ Recruiting

Enrollment open • Dermatology • Dermatopathology • Lichen Planus

Chronic Ulcerative Complications in the Management of Advanced Mycosis Fungoides with Large Cell Transformation (ISDS 2025) - "Though initially treated with localized radiation, methotrexate, bexarotene, and narrowband UVB phototherapy, funding limitations disrupted therapy continuity...Management included total skin electron beam therapy, reintroduction of oral bexarotene (750 mg daily), and topical Triamcinolone, later switched to tazarotene cream...At follow-up, the patient reported significant improvement in skin lesions leg ulcers with partial disease response and no lymphadenopathy or hepatosplenomegaly despite persistent ulceration. This case highlights the challenges of advanced mycosis fungoides with large cell transformation and ulcerations, where the relapsing course of cutaneous T-cell lymphoma necessitates multidisciplinary care, and the leading infectious complication is Staphylococcus aureus-driven cellulitis and bacteremia due to skin barrier disruption."

Metastases • Cutaneous T-cell Lymphoma • Dermatology • Hematological Malignancies • Infectious Disease • Lymphoma • Mycosis Fungoides • Oncology • T Cell Non-Hodgkin Lymphoma • Ulcerative Colitis

The Role of Neutrophils in Cutaneous Immune-Related Adverse Events: A Case of Bullous Pemphigoid in a Patient Undergoing Immunotherapy (ISDS 2025) - " A 77-year-old male with a history of acute bilineal leukemia status-post allogeneic bone marrow transplant in 2016 who developed invasive squamous cell carcinoma of the skin metastasized to bone and was being treated with cemiplimab...Treatment included topical triamcinolone, intravenous corticosteroids, intravenous Immunoglobulin, and dexamethasone rinses for oral lesions... BP is an inflammatory subepidermal blistering disease that may occur as an immunotherapy-related adverse event with neutrophil predominance. This case highlights the potential role of neutrophil-targeted strategies in managing cutaneous irAEs."

Adverse events • Clinical • Bone Marrow Transplantation • Bullous Pemphigoid • Dermatology • Dermatopathology • Hematological Malignancies • Immunology • Leukemia • Non-melanoma Skin Cancer • Pruritus • Squamous Cell Carcinoma • Squamous Cell Skin Cancer

Improvement of Skin Transcriptome and Pruritus within 24 Hours with Topical Triamcinolone in Atopic Dermatitis: A Randomized, Vehicle-Controlled Study (ISDS 2025) - "Triamcinolone, a moderate strength topical corticosteroid, improved pruritus and reversed immune dysregulation in AD patients as early as 24 hours after the first application. These results suggest that transcriptomics data from tape strips could be used to compare efficacy of AD topical treatments as early as 24 hours after application on small skin areas."

Clinical • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Pruritus • CD40LG • CD8 • CXCL6 • CXCL9 • IL1RN • IL22 • IL34 • IL9 • PLCB3 • STAT3

Bullous Fixed Drug Eruption Triggered by Acetaminophen: A Rare Case with Diagnostic Pitfalls (ISDS 2025) - "He was initially diagnosed with bullous pemphigoid and treated with triamcinolone 0.1% cream twice daily...Clinicians should maintain a high index of suspicion for over-the-counter analgesics when evaluating recurrent bullous eruptions. Early identification and avoidance will prevent recurrence, unnecessary tests, and unnecessary prescriptions."

Clinical • Bullous Pemphigoid • Cardiovascular • Chronic Kidney Disease • Dermatitis • Dermatology • Dermatopathology • Hypertension • Immunology • Nephrology • Renal Disease

Treatment-Resistant Eosinophilic Spongiosis Dermatitis in a Patient With Various Comorbidities: A Case Report. (PubMed, Cureus) - "Alongside receiving a thorough cardiovascular exam workup, the patient tried numerous treatments for his rash and the pruritus, including topical triamcinolone, tacrolimus ointment, steroid injections, hydroxyzine, amitriptyline, and, most recently, dupilumab therapy. This case report highlights the complexity of ongoing assessment and treatment, offering guidance for the care of patients with similar presentations. Educational insights obtained from this report include maintaining broad differential diagnoses, the influence of neuropsychiatry and cardiology in dermatology, and the importance of multidisciplinary care."

Journal • Atopic Dermatitis • Cardiovascular • Contact Dermatitis • Dermatitis • Dermatology • Immunology • Mood Disorders • Pain • Pruritus • Psychiatry • Pulmonary Disease • Venous Ulcer

Evening Slide Symposium (ASDP 2025) - "Her eruption was unresponsive to topical urea, ammonium lactate, and petroleum jelly as well as clobetasol ointment 0.05%...He was on tacrolimus, everolimus and prednisone as well as prophylaxis with valgangicolvir and sulfamethoxazole-trimethoprim...She was on methotrexate, adalimumab and prednisone 1mg as needed for joint swelling. She failed treatment with mupirocin, topical steroids, and oral antihistamines...Case 14 Case Summary This 67-year-old male presented with a bullous eruption on the bilateral lower legs, which developed approximately three days after an infusion of tocilizumab for his rheumatoid arthritis, which he had previously received two weeks prior. Topical triamcinolone treatment was not helpful...The provided clinical history was "rule out angioma". Session Chairs"

B Cell Lymphoma • Back Pain • Chronic Lymphocytic Leukemia • Congestive Heart Failure • Contact Dermatitis • Dermatitis • Dermatology • Diabetes • Endocrine Disorders • Gastroenterology • Gastrointestinal Disorder • Grave’s Disease • Heart Failure • Hematological Disorders • Hematological Malignancies • Hypertension • Immunology • Infectious Disease • Inflammatory Arthritis • Inflammatory Bowel Disease • Leukemia • Lyme Disease • Lymphoma • Lymphoplasmacytic Lymphoma • Metabolic Disorders • Musculoskeletal Diseases • Musculoskeletal Pain • Nephrology • Neutropenia • Non-Hodgkin’s Lymphoma • Pruritus • Rare Diseases • Renal Disease • Rheumatoid Arthritis • Rheumatology • Septic Shock • Solid Tumor • Thyroid Gland Carcinoma • Thyroid Gland Papillary Carcinoma • Type 1 Diabetes Mellitus • Type 2 Diabetes Mellitus • Ulcerative Colitis • Waldenstrom Macroglobulinemia

A Case of Granuloma Annulare Mimicking Candidal Intertrigo in the Groin. (PubMed, Cureus) - "The patient was subsequently treated with triamcinolone 0.1% ointment and hydroxychloroquine 200 mg twice daily and is currently pending follow-up. The objective of this report is to highlight an atypical presentation of GA and emphasize the importance of maintaining a broad differential diagnosis for annular skin lesions. Further research is needed to elucidate GA's pathogenesis and optimize treatment strategies for chronic or widespread disease."

Journal • Dermatology • Immunology • Rare Diseases

Cutaneous Mastocytosis with Rising Tryptase Mimicking Drug Allergy in an Infant (ACAAI 2025) - "Case Description A 22-month-old male initially presented at 4 months of age with a persistent, diffuse rash attributed to a drug allergy following an amoxicillin course...Despite treatment with cetirizine, montelukast, and topical triamcinolone, the patient had worsening pruritus and hives, requiring additional antihistamines...This case underscores diagnostic challenges of MPCM in infants, the importance of distinguishing it from mimickers, and the role of biopsy and longitudinal tryptase monitoring in management. Open-evidence was used for content."

Allergy • Dermatology • Immunology • Infectious Disease • Pruritus • Rare Diseases • Urticaria

Therapeutic Effect of Topical Triamcinolone Acetonide Combined With 10600-nm Ablative Fractional Carbon Dioxide Laser or 1565-nm Non-Ablative Fractional Laser on Hypertrophic Scars in the Rabbit Ear Model. (PubMed, Aesthetic Plast Surg) - "AFL and NAFL facilitate the efficacy of topical TAC on HS and regulate inflammation and fibroblast activation."

Journal • Preclinical • Aesthetic Medicine • Inflammation • CD163 • CD68 • IL1B • PTPRC • SMAD3 • TGFB1

Leukocytoclastic Vasculitis in a Patient with Crohn's Disease on Anti-TNF-α Therapy (ACG 2025) - "The patient's adalimumab therapy was discontinued, and a transition was planned to anti-IL-23 therapy with risankizumab, methotrexate and topical triamcinolone acetonide. LCV is a rare small-vessel vasculitis mediated by immune complex deposition in postcapillary venules. While re-challenging with another anti-TNF-α therapy may be considered, the preferred approach for ongoing IBD management in these patients is to switch to a non-TNF-α biologic. Although not as common as other dermatologic AEs of biologic therapies, clinicians should keep LCV on their differential diagnosis when evaluating rashes in IBD patients to promptly identify and implement appropriate management for these cases.Figure: Clinical image of rash on patient's right lower extremity.Figure: Clinical image of rash on patient's left lower extremity"

Clinical • Crohn's disease • Gastroenterology • Genetic Disorders • Immunology • Infectious Disease • Inflammatory Bowel Disease • Rheumatology • Vasculitis • IL23A

Ruxolitinib Cream Versus Triamcinolone Cream in Adults With Mild to Moderate Atopic Dermatitis. (PubMed, J Drugs Dermatol) - "Treatment-emergent adverse events were mild/moderate in severity; nasopharyngitis and headache were most common (n=2 [4.0%] each). In summary, ruxolitinib cream is a well-tolerated nonsteroidal therapy with efficacy at least as good as a midpotency topical corticosteroid while avoiding the potential concerns of long-term corticosteroid use."

Clinical • Journal • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Infectious Disease • Inflammation • Pain

Treatment Outcomes and Patient Satisfaction of Oral Lichen Planus Treatment (clinicaltrials.gov) - P2/3 | N=56 | Recruiting | Sponsor: Dar Al Uloom University | Initiation date: Apr 2024 ➔ Aug 2024

Trial initiation date • Dermatology • Dermatopathology • Lichen Planus

Triamcinolone application following internal urethrotomy for reducing urethral stricture recurrence rate: a systematic review and meta-analysis of randomized controlled trials. (PubMed, Arch Ital Urol Androl) - "Triamcinolone ointment with CIC reduced urethral stricture recurrence following internal urethrotomy, whereas submucosal injection did not. Both treatments do not increase the maximum urinary flow rate."

Clinical • Journal • Retrospective data • Review • Fibrosis • Immunology • Urology

A Spicy Case of Contact Dermatitis to Carvone (EADV 2025) - "Contact allergy was suspected, and she was referred to patch testing while being prescribed triamcinolone ointment and advised to avoid fragranced lipsticks and heavily spiced foods...Contact allergy to hydroperoxide of linalool is common (8.8% in 5,511 patients), while carvone allergy is rarer (0.78%).1,2 As our patient, carvone-positive individuals are most commonly women over 40, with reported cases often linked to oral irritation, dry mouth, contact cheilitis, and lichen planus.2-5 Reports of carvone contact allergy are linked to the use of mint-flavored products, such as toothpaste, rather than dietary sources, making this case noteworthy.3-5 Carvone-containing spices are common in the South Asian diet, emphasizing the importance of patient history. In this case, early identification and avoidance of triggers such as raw fennel seeds and peppermint resulted in a successful outcome."

Clinical • Contact Dermatitis • Dermatitis • Dermatology • Dermatopathology • Immunology • Lichen Planus • Xerostomia

Efficacy of Ceramide-Containing Moisturizer in Multivesicular Emulsion as a Steroid-Sparing Agent in Patients with Atopic Dermatitis: A Prospective Randomized Controlled Trial (EADV 2025) - "Participants were randomized to apply either a ceramide-containing cream in MVE or a simple cream base twice daily for 4 weeks, with 0.1% triamcinolone acetonide cream for as- needed use... Addition of topical moisturizers demonstrated efficacy in reducing topical corticosteroid use, improving clinical outcomes and enhancing skin barrier, with a more rapid onset of these effects from ceramide-containing MVE cream compared to a simple cream base. This earlier therapeutic response highlights its benefits as a safe and effective steroid-sparing adjunctive therapy for patients with mild-to-moderate AD."

Clinical • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Grover's disease-like lesions associated to immune check point inhibitors (EADV 2025) - " This study presents two cases of GD-like lesions triggered by ICPI, specifically nivolumab and durvalumab/tremelimumab...The complete eruption resolved with topical triamcinolone acetonide and oral antihistamines...Treatment with prednisone and antihistamines resulted in significant improvement... This article highlights the importance of keeping GD-like lesions in the differential diagnosis when approaching an oncologic patient under ICPI with a maculopapular eruption. In these cases, taking a biopsy may be determinant in patient´s prognosis, as the results of the histopathological analysis can provide the clinician with key information to make decisions regarding the continuation of the oncological treatment, which, in the end, will have an important impact on the patient's prognosis and quality of life. GD-like lesions in the context of ICPI are usually self-limiting, allowing the continuation of oncologic treatment."

Dermatology • Oncology • Pruritus

Treatment Outcomes and Patient Satisfaction of Oral Lichen Planus Treatment (clinicaltrials.gov) - P2/3 | N=56 | Recruiting | Sponsor: Dar Al Uloom University | Active, not recruiting ➔ Recruiting | Initiation date: Apr 2023 ➔ Apr 2024

Enrollment open • Trial initiation date • Dermatology • Dermatopathology • Lichen Planus

Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus (clinicaltrials.gov) - P4 | N=60 | Not yet recruiting | Sponsor: All India Institute of Medical Sciences, Bhubaneswar

New P4 trial • Dermatology • Dermatopathology • Lichen Planus

Persistent Lichenoid Reaction and Eruptive Keratoacanthomas Following PD-1 Inhibitor Therapy. (PubMed, HCA Healthc J Med) - "Immune checkpoint inhibitors, such as nivolumab, have become integral in treating metastatic malignancies by enhancing immune responses against tumors...Treatment with triamcinolone cream 0.1% provided limited relief...Oral prednisone 10 mg daily for 14 days yielded temporary improvement...Further KAs emerged and were treated and resolved with intralesional 5-fluorouracil...Persistent lichenoid dermatitis and eruptive KAs present unique challenges, requiring tailored therapeutic strategies. Further research is essential to optimize management of these adverse events and improve patient outcomes."

Journal • Cutaneous Melanoma • Dermatitis • Dermatology • Immunology • Melanoma • Oncology • Solid Tumor

Neomycin sulfate and triamcinolone acetonide suspended ointment designed for transdermal delivery: formulation and in vitro evaluation. (PubMed, Saudi Pharm J) - "The present study aimed to investigate the relationship between formulation/process variables versus the content uniformity and viscosity of neomycin sulfate and triamcinolone acetonide ointments and to explore the feasibility of using an in vitro approach to assess product sameness. Furthermore, skin irritation tests demonstrated that the formulation caused no detectable irritation. These results demonstrate that it can be a promising drug in treating neurodermatitis and chronic eczema."

Journal • Preclinical • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Infectious Disease

Sitagliptin Induced Bullous Pemphigoid-A Rare But Devious Side Effect (ENDO 2025) - "Initially, the etiology of blisters was thought to be infectious, however, a short course of doxycycline didn't show any improvement...He started on methylprednisolone initially, later switched to oral prednisone...The patient was discharged on steroid taper and topical triamcinolone resulted in full resolution of the bullae in 2 weeks. Immunobullous disorders, most commonly bullous pemphigoid, is being recorded as a commonly emerging side effect of DPP-4 inhibitors...Prompt withdrawal of the offending agent, along with immunosuppressive therapy, most commonly steroids, can result in swift clinical response. Therefore a high suspicion is a prerequisite for rapid diagnosis and prompt discontinuation of the offending agent for best outcomes."

Adverse events • Late-breaking abstract • Asthma • Bullous Pemphigoid • Cardiovascular • Dermatology • Dermatopathology • Diabetes • Dyslipidemia • Hypertension • Immunology • Metabolic Disorders • Pruritus • Respiratory Diseases • Type 2 Diabetes Mellitus

Comparison of Subconjunctival Triamcinolone with Topical Prednisolone for Routine Anti-Inflammatory Prophylaxis in Manual Small Incision Cataract Surgery: A Single-Center, Randomized Controlled Trial Pilot Protocol. (PubMed, Clin Ophthalmol) - P=N/A | "Subconjunctival injection of triamcinolone acetonide (TA) is an effective method to prevent postoperative inflammation in phacoemulsification eyes...Intracameral moxifloxacin 0.15% is injected at the end of surgery in both groups...The objective of this study is to evaluate the safety and efficacy of a single subconjunctival TA injection compared to standard postoperative topical therapy using PA 1% in eyes undergoing MSICS. Clinicaltrials.gov: NCT05248139; Protocol issue date: August 9, 2024; Amendment number: 02."

Journal • Cataract • Inflammation • Macular Edema • Ocular Infections • Ocular Inflammation • Ophthalmology • Uveitis

Glucocorticoid withdrawal syndrome: Disproportionality analysis of cases using VigiBase data. (PubMed, Daru) - "Abrupt withdrawal of glucocorticoid therapy may cause GWS. Healthcare providers should inform patients about the potential risks of withdrawal, particularly when prescribing topical hydrocortisone and betamethasone, topical and nasal triamcinolone, and oral and topical cortisone, to promote safer practices."

Journal