dual ATR-mTOR inhibitor / Rakovina Therap, Variational AI - LARVOL DELTA

Dual ATR-mTOR inhibitors for PTEN-deficient prostate cancer (EORTC-NCI-AACR 2026) - "Abstract will be available as of 4 November (with consent of the author)"

Genito-urinary Cancer • Oncology • Prostate Cancer • Solid Tumor • PTEN

Brain-penetrant dual ATR-mTOR inhibitors for PTEN-deficient cancers (SNO 2026) - No abstract available

Oncology • PTEN

A novel brain-penetrant dual ATR-mTOR inhibitor for PTEN-deficient cancers (AACR 2026) - "The most promising molecules were synthesized and tested, and data on potency, selectivity, ADME and in vivo efficacy will be presented. Enki™ has enabled deep exploration of chemical space and rapid generation of de novo molecules, accelerating the drug discovery process and allowing discovery and development of CNS-penetrating dual ATR and mTOR inhibitors."

Brain Cancer • Breast Cancer • Glioma • Oncology • Solid Tumor • CHEK1 • PTEN