dual ATR-mTOR inhibitor / Rakovina Therap, Variational AI - LARVOL DELTA

A novel brain-penetrant dual ATR-mTOR inhibitor for PTEN-deficient cancers (AACR 2026) - "The most promising molecules were synthesized and tested, and data on potency, selectivity, ADME and in vivo efficacy will be presented. Enki™ has enabled deep exploration of chemical space and rapid generation of de novo molecules, accelerating the drug discovery process and allowing discovery and development of CNS-penetrating dual ATR and mTOR inhibitors."

Brain Cancer • Breast Cancer • Glioma • Oncology • Solid Tumor • CHEK1 • PTEN