jankistomig (OTP-01) / Ottimo Pharma - LARVOL DELTA

A Study of OTP-01, a Dual Paratopic PD-1/VEGFR2 Antibody, in Patients With Advanced Solid Tumors (clinicaltrials.gov) - P1/2 | N=170 | Not yet recruiting | Sponsor: Ottimo Pharma Limited

New P1/2 trial • Solid Tumor

Lotte Biologics wins UK contract for antibody drug manufacturing, aims for more orders (Chosun Biz) - "Lotte Biologics has won a contract for contract manufacturing organization (CMO) for a dual antibody new drug candidate being developed by OTTIMO Pharma in the United Kingdom. This is the second contract win in about two months, following the agreement in April with an Asia-based corporation for the production of a candidate for clinical trials of an antibody-drug conjugate (ADC)....Jankistomig is a dual antibody that targets the protein PD-L1, which cancer cells use to disguise themselves as normal cells, and the vascular endothelial growth factor (VEGF) that promotes tumor growth. Under this contract, Lotte Biologics will produce the active pharmaceutical ingredient for jankistomig at its Syracuse plant in New York, USA."

Licensing / partnership • Oncology