Trijardy XR (empagliflozin/linagliptin/metformin XR) / Eli Lilly, Boehringer Ingelheim - LARVOL DELTA

Trijardy XR-A New 3-Drug Combination for Type 2 Diabetes. (PubMed, JAMA) - No abstract available

Journal • Diabetes • Metabolic Disorders • Type 2 Diabetes Mellitus

In brief: Trijardy XR - a new 3-drug combination for Type 2 diabetes. (PubMed, Med Lett Drugs Ther) - No abstract available

Journal • Diabetes • Metabolic Disorders • Type 2 Diabetes Mellitus

Triple fixed-dose combination empagliflozin, linagliptin, and metformin for patients with type 2 diabetes. (PubMed, Postgrad Med) - "The evaluated doses of empagliflozin/linagliptin/metformin XR FDC tablets were bioequivalent to the corresponding free combinations. Based on these two bioequivalence studies and existing phase 3 data, the FDA has recently approved this triple FDC to improve glycemic control in adults with T2D."

Clinical • Journal • Diabetes • Metabolic Disorders • Type 2 Diabetes Mellitus

New combination drug: Trijardy approved by FDA (diaTribe) - ''Dr. Ralph DeFronzo (who was responsible for some of the development of the SGLT-2 inhibitor 'class' of drugs) is quoted in Lilly’s press release about Trijardy XR. He says that many people with type 2 diabetes need more than one medication to help them manage their blood glucose levels – and, we’d add, to assist in providing heart health benefits. Giving people a way to take several medications in one pill makes a treatment less burdensome for many. As Dr. DeFronzo says, '… having three different diabetes medications in a single tablet is an important advance in diabetes treatment.'''

Media quote • Regulatory

FDA OKs new triple-combo pill, Trijardy XR, for type 2 diabetes (Medscape) - "'Type 2 diabetes is a complex disease that often requires the use of multiple antidiabetic medications to improve glycemic control. Having three different diabetes medications in a single tablet is an important advance in diabetes treatment,' Ralph DeFronzo, MD...said in the release."

Media quote • Regulatory

FDA approves first triple combination pill for type 2 diabetes (Healio) - "'Many adults living with type 2 diabetes who are already on a treatment plan including multiple medications still struggle to keep their blood sugar under control, and may require additional agents to reach their [HbA1c] targets,' Ralph A. DeFronzo, MD...said in the release. "

Media quote • Regulatory