LW402 / Shanghai Longwood Biopharmaceuticals - LARVOL DELTA

Efficacy and Safety of LW402, A Novel Highly Selective JAK1 Inhibitor, in Adults with Moderate-to-Severe Atopic Dermatitis: Results from a Randomized, Double-blind, Placebo-controlled Phase II Trial (EADV 2026) - No abstract available

Clinical • P2 data • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Evaluation of the Efficacy and Safety of Oral LW402 Tablets for the Treatment of Patients With Moderate-to-Severe Atopic Dermatitis (clinicaltrials.gov) - P3 | N=480 | Recruiting | Sponsor: Shanghai Longwood Biopharmaceuticals Co., Ltd. | Not yet recruiting ➔ Recruiting

Enrollment open • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Safety, tolerability, pharmacokinetics, and pharmacodynamics of LW402, a preferential Janus kinase 1 inhibitor in healthy volunteers: a randomized, double-blinded, placebo-controlled phase 1 trial. (PubMed, Front Pharmacol) - "LW402's favorable safety profile, predictable PK characteristics, and selective JAK1 inhibition collectively support its continued development for the treatment of autoimmune diseases. http://www.chinadrugtrials.org.cn, identifier CTR20201897."

Clinical • Journal • P1 data • PK/PD data • Cardiovascular • Immunology

Evaluation of the Efficacy and Safety of LW402 Tablets in Patients With Non-Segmental Vitiligo (clinicaltrials.gov) - P2 | N=180 | Not yet recruiting | Sponsor: Shanghai Longwood Biopharmaceuticals Co., Ltd.

New P2 trial • Dermatology • Immunology • Vitiligo

Evaluation of the Efficacy and Safety of Oral LW402 Tablets for the Treatment of Patients With Moderate-to-Severe Atopic Dermatitis (clinicaltrials.gov) - P3 | N=480 | Not yet recruiting | Sponsor: Shanghai Longwood Biopharmaceuticals Co., Ltd.

New P3 trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Phase II Study of LW402 in Moderate-to-Severe Atopic Dermatitis (clinicaltrials.gov) - P2 | N=144 | Completed | Sponsor: Shanghai Longwood Biopharmaceuticals Co., Ltd.

New P2 trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology