SUVN-6206012
/ Suven Life Sci
- LARVOL DELTA
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October 10, 2022
In vivo Efficacy of SUVN-6206012 (P2X7R antagonist) on Chronic Constriction Injury Induced Neuropathic Pain in Two Different Species
(Neuroscience 2022)
- "Interestingly, in vivo efficacy data is in congruent with in vitro affinity, like increase in PWTs are relatively higher in mice when compared with rats. These results further support that SUVN-6206012 may translate similar in vivo efficacy in the clinic due to its higher binding affinity towards P2X7 receptors in human."
Preclinical • CNS Disorders • Neuralgia • Pain
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