fimasartan/indapamide FDC (BR1015) / Boryung Group - LARVOL DELTA

Efficacy and Safety of Fimasartan/Indapamide Combination Therapy versus Fimasartan Monotherapy in Patients with Essential Hypertension Inadequately Responding to Fimasartan 30 mg (FINEDUO): A Randomized, Double-Blind, Multicenter, Phase III Study. (PubMed, Drug Des Devel Ther) - P3 | "This regimen may serve as an effective therapeutic option, particularly in elderly or high-risk hypertensive patients. https://www.clinicaltrials.gov, NCT05878561."

Clinical • Journal • Monotherapy • P3 data • Cardiovascular • Hypertension

A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015-A and Co-administration of BR1015-3 and BR1015-2 Under Fasting Conditions (clinicaltrials.gov) - P1 | N=58 | Not yet recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd

New P1 trial • Cardiovascular • Hypertension

A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015-A and Co-administration of BR1015-1 and BR1015-2 Under Fasting Conditions (clinicaltrials.gov) - P1 | N=58 | Not yet recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd

New P1 trial • Cardiovascular • Hypertension

A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015-A and Co-administration of BR1015-3 and BR1015-2 Under Fed Conditions (clinicaltrials.gov) - P1 | N=48 | Not yet recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd

New P1 trial • Cardiovascular • Hypertension

A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015-A and Co-administration of BR1015-1 and BR1015-2 Under Fed Conditions (clinicaltrials.gov) - P1 | N=48 | Not yet recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd

New P1 trial • Cardiovascular • Hypertension

BR-FIC-CT-104: A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-3 and BR1015-2 Under Fed Conditions (clinicaltrials.gov) - P1 | N=49 | Completed | Sponsor: Boryung Pharmaceutical Co., Ltd | Active, not recruiting ➔ Completed

Trial completion • Cardiovascular • Hypertension

BR-FIC-CT-103: A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-3 and BR1015-2 Under Fasting Conditions (clinicaltrials.gov) - P1 | N=60 | Completed | Sponsor: Boryung Pharmaceutical Co., Ltd | Active, not recruiting ➔ Completed

Trial completion • Cardiovascular • Hypertension

BR-FIC-CT-105: A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-1 and BR1015-2 Under Fasting Conditions (clinicaltrials.gov) - P1 | N=58 | Completed | Sponsor: Boryung Pharmaceutical Co., Ltd | Active, not recruiting ➔ Completed

Trial completion • Cardiovascular • Hypertension

BR-FIC-CT-106: A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-1 and BR1015-2 in Healthy Volunteers Fed Conditions (clinicaltrials.gov) - P1 | N=48 | Completed | Sponsor: Boryung Pharmaceutical Co., Ltd | Active, not recruiting ➔ Completed

Trial completion • Cardiovascular • Hypertension

BR-FIC-CT-104: A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-3 and BR1015-2 Under Fed Conditions (clinicaltrials.gov) - P1 | N=49 | Active, not recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd | Not yet recruiting ➔ Active, not recruiting

Enrollment closed • Cardiovascular • Hypertension

BR-FIC-CT-103: A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-3 and BR1015-2 Under Fasting Conditions (clinicaltrials.gov) - P1 | N=60 | Active, not recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd | Not yet recruiting ➔ Active, not recruiting

Enrollment closed • Cardiovascular • Hypertension

BR-FIC-CT-106: A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-1 and BR1015-2 in Healthy Volunteers Fed Conditions (clinicaltrials.gov) - P1 | N=48 | Active, not recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd | Not yet recruiting ➔ Active, not recruiting

Enrollment closed • Cardiovascular • Hypertension

BR-FIC-CT-105: A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-1 and BR1015-2 Under Fasting Conditions (clinicaltrials.gov) - P1 | N=58 | Active, not recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd | Not yet recruiting ➔ Active, not recruiting

Enrollment closed • Cardiovascular • Hypertension

A Study to Evaluate the Efficacy and Safety of BR1015 Combination Therapy (clinicaltrials.gov) - P3 | N=248 | Completed | Sponsor: Boryung Pharmaceutical Co., Ltd | Recruiting ➔ Completed

Monotherapy • Trial completion • Cardiovascular • Hypertension

A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-3 and BR1015-2 Under Fed Conditions (clinicaltrials.gov) - P1 | N=48 | Not yet recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd

New P1 trial • Cardiovascular • Hypertension

A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-1 and BR1015-2 Under Fasting Conditions (clinicaltrials.gov) - P1 | N=58 | Not yet recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd

New P1 trial • Cardiovascular • Hypertension

A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-3 and BR1015-2 Under Fasting Conditions (clinicaltrials.gov) - P1 | N=58 | Not yet recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd

New P1 trial • Cardiovascular • Hypertension

A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-1 and BR1015-2 in Healthy Volunteers Fed Conditions (clinicaltrials.gov) - P1 | N=48 | Not yet recruiting | Sponsor: Boryung Pharmaceutical Co., Ltd

New P1 trial • Cardiovascular • Hypertension

A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1015" and Co-administration of "BR1015-1" and "BR1015-2" Under Fasting Conditions in Healthy Volunteers (clinicaltrials.gov) - P1 | N=57 | Completed | Sponsor: Boryung Pharmaceutical Co., Ltd | Active, not recruiting ➔ Completed

Trial completion • Cardiovascular • Hypertension