hemophilia A cell therapy / Sernova Biotherapeutics - LARVOL DELTA

Sernova Announces Peer Reviewed Publication Demonstrating Safety and Efficacy of a Novel Cell Pouch Cell Therapy Approach for Treatment of Severe Hemophilia A (Sernova Press Release) - "Sernova Corp...is pleased to announce a peer reviewed published scientific journal article highlighting successful development of a novel cell therapy approach for treatment of severe hemophilia A , a serious genetic bleeding disorder caused by missing factor VIII (FVIII) activity in the blood stream. The journal article...was published in the prestigious scientific journal, Molecular Therapy: Methods & Clinical Development, Volume 23, December 2021."

Preclinical • Genetic Disorders • Hemophilia

[VIRTUAL] Combined Gene and Cell Therapy for the Treatment of Hemophilia A within an Implantable Therapeutic Device (ISTH 2020) - "Overall, these results pave the way for future human clinical testing in HA patients by transplantation of GMP produced autologous gene corrected BOECs within implanted device."

Gene Therapies • Hematological Disorders • Hemophilia • Oncology • Rare Diseases • Transplantation

AgeX Therapeutics and Sernova to collaborate to engineer universal locally immune protected cell therapies for type I diabetes and hemophilia A (Businesswire) - "AgeX Therapeutics, Inc....and Sernova Corp....announced today a research collaboration where Sernova will utilize AgeX’s UniverCyteTM gene technology to generate immune-protected universal therapeutic cells for use in combination with Sernova’s Cell PouchTM for the treatment of type I diabetes and hemophilia A. The goal is to eliminate the need for immunosuppressive medications following Cell Pouch cell transplantation....Pluripotent stem cell-derived or adult donor-derived human Factor VIII-releasing cells modified with AgeX’s UniverCyte will be evaluated in Sernova’s hemophilia A program."

Licensing / partnership • Hemophilia

"AgeX Therapeutics and Sernova to Collaborate to Engineer Universal Locally Immune Protected Cell Therapies for Type I Diabetes and Hemophilia A https://t.co/Ic1PFRy5VN" (@NewsFromBW)

Diabetes • Gene Therapies • Hematological Disorders • Hemophilia • Metabolic Disorders • Rare Diseases

[VIRTUAL] Combined gene and cell therapy for the treatment of hemophilia A within an implantable therapeutic device (ISTH 2020) - "Full abstracts will be available June 29, 2020 at 9:00 AM U.S. Eastern Time"

Gene Therapies • Genetic Disorders • Hematological Disorders • Hemophilia • Rare Diseases