C9ORF72-ALS therapeutic / Locana - LARVOL DELTA

Locanabio Presents Preclinical Data from its Vectorized snRNA Exon Skipping Program for DMD and Cas13d Multi-targeting Program for C9orf72 ALS at the American Society of Gene and Cell Therapy (ASGCT) 26th Annual Meeting (BioSpace) - "Locanabio...announced the presentation of data from its lead vectorized snRNA exon skipping program, LBIO-115, in development for the treatment of Duchenne muscular dystrophy (DMD). A second presentation highlights data from the company’s Cas13d multi-targeting program for C9orf72-related amyotrophic lateral sclerosis (ALS). The ASGCT 26th Annual Meeting is being held May 16-20, in Los Angeles. 'The preclinical data presented at the ASGCT meeting highlight Locanabio’s expertise in therapeutic RNA modification with two different payloads from our versatile drug development platform: our proprietary vectorized snRNAs and Cas13d which are designed to durably address disease causing RNA using different mechanisms.'"

Preclinical • Amyotrophic Lateral Sclerosis • CNS Disorders