NILK-2501
/ LightChain Bioscience, LamKap Bio
- LARVOL DELTA
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February 15, 2023
Novel GPC3xCD3 (NILK-2501) and GPC3xCD28 (NILK-3801) κλ Bispecific Antibodies for Next Generation Immunotherapy of GPC3-Expressing Solid Cancers
(APASL 2023)
- "The superagonistic monoclonal anti-human CD28 antibody (IgG4κ) TGN1412 was used as comparator. Activity is maintained while it allows well tailorable dose response with reduced cytokine release. Compounds are currently in extensive pre-clinical assessment 999"
IO biomarker • Gastrointestinal Cancer • Hepatocellular Cancer • Hepatology • Liver Cancer • Oncology • Solid Tumor • CD4 • CD8 • GPC3 • IL6 • TNFA
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