Bisono Tape (bisoprolol transdermal) / Toa Eiyo, Nitto Denko - LARVOL DELTA

Tachycardia-Induced Cardiomyopathy Following Prolonged Ritodrine Infusion During Pregnancy: A Case Report. (PubMed, Cureus) - "Administration of adenosine and verapamil revealed atrial tachycardia or flutter, and the patient was diagnosed with tachycardia-induced cardiomyopathy, which was confirmed by a dramatic improvement in systolic function following maternal heart rate control using a bisoprolol patch. The patient delivered a healthy female via cesarean section at 37 weeks of gestation and was discharged from the hospital with favorable maternal and neonatal outcomes. This report highlights another potential risk of maternal cardiac deterioration due to beta-adrenergic effects, emphasizing the importance of reconsidering the long-term use of ritodrine infusion, as well as the need for dose titration, discontinuation, or switching to the alternative agent in cases of persistent or exacerbated tachycardia. Careful monitoring, including more frequent daily checkups to assess pulse rate and respiratory changes, along with the use of early warning systems and occasional BNP or NT-proBNP..."

Journal • Cardiomyopathy • Cardiovascular • CNS Disorders • Developmental Disorders • Psychiatry • Ventricular Tachycardia

Innovative Long-Acting Bisoprolol Patch: Synergistic Ion-Pair Skin Adsorption for Drug Delivery Control Coupled with Dynamic Modulation of Penetration Enhancers. (PubMed, Mol Pharm) - "This strategy aims to rapidly reduce blood pressure in the initial phase with subsequent weakening of IPM disruption, allowing the ion-pairing strategy to dominate drug delivery control and maintain stable long-term therapeutic effects. Pharmacokinetic studies demonstrated that the newly developed BSP sustained release patch maintains stable blood drug concentrations, reduces burst release effects, increases bioavailability to 84.679%, doubles MRT0-t, halves Cmax, and significantly reduces the occurrence of blood pressure fluctuations."

Journal

Transdermal bisoprolol for prevention of postoperative atrial fibrillation: A systematic review and meta-analysis. (PubMed, J Arrhythm) - "The heterogeneity of the included studies limits certain interpretations. Future randomized clinical trials may elucidate the superiority of transdermal administration over oral administration."

Clinical • Journal • Retrospective data • Review • Atrial Fibrillation • Cardiovascular

A case of reinitiation of modified electroconvulsive therapy 2 weeks after modified electroconvulsive therapy-induced Takotsubo cardiomyopathy in a male patient with major depressive disorder. (PubMed, PCN Rep) - "We confirmed that the cardiac function had been normalized, applied a bisoprolol fumarate patch as a preventive measure, and reinitiated ECT 14 days after the onset of TCM...Therefore, TCM should be recognized as a side-effect of ECT, even in men. Moreover, depending on whether the patient's condition is stable, ECT can be successfully performed in patients with TCM."

Journal • Acute Coronary Syndrome • Cardiomyopathy • Cardiovascular • CNS Disorders • Congestive Heart Failure • Depression • Heart Failure • Major Depressive Disorder • Mood Disorders • Pain • Psychiatry

A Comparative Study to Investigate the Effects of Bisoprolol in Patients with Chronic Heart Failure and Hypertension When Switched from Tablets to Transdermal Patches. (PubMed, J Pers Med) - "Compared with oral bisoprolol, the bisoprolol transdermal patch lowers HR at 06:00 and inhibits the onset of PVCs during sleep and in the morning."

Journal • Cardiovascular • Congestive Heart Failure • Heart Failure • Hypertension

Managing postoperative atrial fibrillation after open-heart surgery using transdermal β blockers. (PubMed, J Cardiothorac Surg) - "Single-use bisoprolol transdermal patch may help control the heart rate during the initial treatment of POAF after open-heart surgery."

Journal • Surgery • Atrial Fibrillation • Cardiovascular

Lichenoid drug eruption associated with bisoprolol transdermal patches. (PubMed, Contact Dermatitis) - No abstract available

Journal • Lichen Planus

The influence of edema on the bisoprolol blood concentration after bisoprolol dermal patch application: A case-control study. (PubMed, Medicine (Baltimore)) - "In this study, the blood concentration of bisoprolol and its heart rate-reducing effects after bisoprolol dermal patch application might not be affected by systemic edema in the lower extremities."

Clinical • Journal • Cardiovascular • Critical care

Strange coincidence in the gut: Pseudomelanosis duodeni diagnosed by capsule endoscopy and active bleeding due to angiodysplasia. (PubMed, Rev Esp Enferm Dig) - "He was under therapy with hydralazine, furosemide, amlodipine, valsartan, nitroglycerin patches, bisoprolol, omeprazole, doxazosin, human insulin and oral iron. Three months later, he suffered from a new episode of bleeding and consequently, a small bowel capsule endoscopy (SBCE) was indicated. It was reported a gastric and duodenal mucosa with an intense speckled black pigmentation, compatible with pseudomelanosis."

Journal • Cardiovascular • Chronic Kidney Disease • Coronary Artery Disease • Diabetes • Dyslipidemia • Heart Failure • Hematological Disorders • Hypertension • Metabolic Disorders • Renal Disease

Impact of bisoprolol transdermal patch on early recurrence during the blanking period after atrial fibrillation ablation. (PubMed, J Arrhythm) - "Administering BTPs was an independent factor that protected against ERAAs (odds ratio 0.181, [95% confidence interval 0.059-0.559], P = .003). BTPs may prevent ERAAs after ablation."

Journal • Atrial Fibrillation • Cardiovascular

Preventative effects of bisoprolol transdermal patches on postoperative atrial fibrillation in high-risk patients undergoing non-cardiac surgery: A subanalysis of the MAMACARI study. (PubMed, J Cardiol) - "Low dose of a bisoprolol patch in the perioperative period was effective for prevention of POAF after non-cardiac surgery in high-risk patients, while long surgery time was an independent risk factor for POAF. It is expected that low dose of a bisoprolol patch can prevent POAF without causing hypotension."

Clinical • Journal • Atrial Fibrillation • Cardiovascular • Hypertension • Hypotension

Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies. (PubMed, Pharmaceutics) - "Finally, results showed the successful utility of permeation enhancers combined with iontophoresis in significantly enhanced transdermal permeation of BH, despite its large molecular weight and hydrophilic nature. Therefore, this strategy could be employed as a successful alternative route of administration to conventional oral tablets."

Journal • PK/PD data • Preclinical • Cardiovascular • Hypertension

Comparison of heart rate reduction effect and safety between bisoprolol transdermal patch and bisoprolol fumarate oral formulation in Japanese patients with persistent/permanent atrial fibrillation (BISONO-AF study). (PubMed, J Cardiol) - "In Japanese patients with persistent or permanent AF, TY 4mg and TY 8mg had heart rate-reducing effects similar to those of BO 2.5mg and BO 5mg, respectively."

Clinical • Journal