obeticholic acid / Sino Biopharm - LARVOL DELTA

Immobilization of tryptophan synthase on a magnetic bead-T4 capsid biocarrier for multi-round biocatalysis producing high-value L-tryptophan analogs. (PubMed, J Biotechnol) - "This platform merges high catalytic efficiency, operational robustness, and cost accessibility, offering a scalable solution for green manufacturing. The modular MBTCB strategy holds broad potential for multi-enzyme cascades and continuous-flow bioreactors, advancing sustainable biocatalysis for chiral chemical synthesis."

Journal

A Phase III Clinical Trial of NTQ1062 in Combination With Fulvestrant for the Treatment of Advanced or Metastatic HR+/HER2- Breast Cancer (clinicaltrials.gov) - P3 | N=210 | Not yet recruiting | Sponsor: Nanjing Chia-tai Tianqing Pharmaceutical

New P3 trial • Breast Cancer • HER2 Breast Cancer • HER2 Negative Breast Cancer • Hormone Receptor Positive Breast Cancer • Oncology • Solid Tumor • HER-2

Efficacy and Safety of Obeticholic Acid in the Treatment of Primary Biliary Cholangitis (clinicaltrials.gov) - P3 | N=108 | Completed | Sponsor: Nanjing Chia-tai Tianqing Pharmaceutical | Recruiting ➔ Completed | N=156 ➔ 108

Enrollment change • Trial completion • Hepatology • Immunology • Primary Biliary Cholangitis

Advances in Treatment of Primary Biliary Cholangitis (PBC) : Episode 10: Current Treatments for PBC (HCPLive) - "Experts reviews the current treatment landscape for management of PBC, highlighting ursodeoxycholic acid (UDCA) and obeticholic acid (OCA), as well as liver transplant."

Video