clozapine orally disintegrating tablets / Generic mfg. - LARVOL DELTA

Study of the Effect of Dosing on Clozapine Levels (clinicaltrials.gov) - P4; N=0; Withdrawn; Sponsor: University of British Columbia; N=50 ➔ 0; Active, not recruiting ➔ Withdrawn

Clinical • Enrollment change • Trial withdrawal • CNS Disorders • Psychiatry • Schizophrenia

[VIRTUAL] Clozapine Combination with Long-Acting Injectable Antipsychotics and Compliance Enhancing Formulations in Treatment-Resistant Schizophrenia: A Literature Review and A Case Series (SIRS 2021) - "However, they are often preferred to “save the day” and there are very few clinical data on their efficacy. These results suggest that there is an urgent need for well-designed, controlled studies of C+LAI."

Clinical • Review • CNS Disorders • Schizophrenia

[VIRTUAL] Clozapine Combination with Long-Acting Injectable Antipsychotics and Compliance Enhancing Formulations in Treatment-Resistant Schizophrenia: A Literature Review and A Case Series (SIRS 2021) - "However, they are often preferred to “save the day” and there are very few clinical data on their efficacy. These results suggest that there is an urgent need for well-designed, controlled studies of C+LAI."

Clinical • Review • CNS Disorders • Schizophrenia

"@JazzPharma is there announcement about end of manufacturing for fazaclo odt? Asking for a patient who was told this today by @Walgreens in #AustinTX" (@bnhall)

Clinical

ANALYSIS OF MEDICAL SERVICES AND DRUG UTILIZATION IN PATIENTS WITH SCHIZOPHRENIA (ISPOR 2019) - "According to the frequency of prescriptions, the top 5 anti-schizophrenia drugs in the clinical use were olanzapine oral sustained release dosage form, risperidone oral sustained release dosage form, clozapine oral sustained release dosage form, quetiapine oral sustained release dosage form, paliperidone sustained release controlled release dosage form. CONCLUSIONS : According to the data of hospitalization and outpatient, the average annual medical expenses of schizophrenia patients in the sample population was 20879.72 RMB, and the average annual hospitalization days was 95.58 days. The most frequently used drug was clozapine oral sustained-release dosage form, followed by risperidone oral sustained-release dosage form and olanzapine oral sustained-release dosage form."

Clinical

FDA: Important updates to the clozapine REMS program (eMPR) - "According to the Food and Drug Administration (FDA), prescribers and pharmacies must be certified in the Clozapine REMS program by February 28, 2019 in order to continue to prescribe or dispense clozapine....Products covered under the Clozapine REMS program include Clozaril (HLS Therapeutics), Fazaclo (Jazz), and Versacloz (TruPharma), in addition to all generic versions."

FDA event